HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

5'-amino-5'-deoxyadenosine

Also Known As:

5'-deoxy-5'-aminoadenosine

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        Deoxyadenosines: 1
        5'-amino-5'-deoxyadenosine: 4
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - Deoxyadenosines: 1
        5'-amino-5'-deoxyadenosine: 4
  - Deoxyribonucleosides: 34
    - Deoxyadenosines: 1
      - 5'-amino-5'-deoxyadenosine: 4

Experts

1.	Christiansen, Michael A: 1 article (05/2009)
2.	Oliveira, Marcelio: 1 article (05/2009)
3.	Peterson, Matt A: 1 article (05/2009)

Related Diseases

1.	Hyperalgesia 11/19/1999 - "In the present study, we examined the antinociceptive and anti-inflammatory effects produced by the peripheral (intraplantar) administration of 5'-amino-5'-deoxyadenosine (an adenosine kinase inhibitor), 2'-deoxycoformycin (an adenosine deaminase inhibitor), and combinations of both agents in the carrageenan-induced thermal hyperalgesia and paw oedema model in the rat. "
2.	Weight Loss (Weight Reduction) 11/27/1998 - "Additionally, 5'-amino-5'-deoxyadenosine significantly reduces withdrawal-induced diarrhea and weight loss. "
3.	Tremor (Tremors) 11/27/1998 - "Mice then receive parenteral treatment with adenosine kinase inhibitors, either 5'-amino-5'-deoxyadenosine (2, 5, 20, 40 mg/kg, intraperitoneal or i.p.) or iodotubericidin (1, 2, 5 mg/kg, i.p.), followed by naloxone injection and opiate withdrawal signs are measured over 20 min. Both adenosine kinase inhibitors significantly reduce the following opiate withdrawal signs in a dose-dependent manner compared to vehicle: withdrawal jumps, teeth chattering, forepaw tremors, and forepaw treads. "
4.	Seizures (Absence Seizure) 06/01/1999 - "The AK inhibitors 5'-amino-5'-deoxyadenosine, 5-iodotubercidin, and 5'-deoxy-5-iodotubercidin inhibited maximal electroshock (MES) seizures in rats. "
5.	Neoplasms (Cancer) 05/01/2009 - "Two novel N(6),5'-bis-ureido 5'-amino-5'-deoxyadenosine derivatives are shown to inhibit tumor cell growth in the NCI 60 human tumor cell panel. "

Related Drugs and Biologics

1.	Adenosine Kinase
2.	Pentostatin (Nipent)
3.	Carrageenan
4.	Adenosine Deaminase
5.	Opiate Alkaloids
6.	Naloxone (Narcan)
7.	5'-deoxy-5-iodotubercidin
8.	5-iodotubercidin