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platinum(II) pentamidine

structure given in first source

Also Known As:

Pt-pent; Pt-pentamidine complex; cis-Pt pentamidine iodide; cis-Pt(II) pentamidine; cis-platinum pentamidine iodide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - platinum(II) pentamidine: 3
- Amidines: 14
  - Benzamidines: 5
    - Pentamidine: 1147
      - platinum(II) pentamidine: 3

Related Diseases

1.	Trypanosomiasis 06/01/1993 - "Cis-Pt pentamidine iodide was active at 5 mgl.kg-1 in one single dose both in mouse and sheep trypanosomiasis models. " 01/01/1990 - "The trypanocidal activity of cis-Pt(II) pentamidine had been demonstrated during the first phase of Trypanosoma brucei brucei sheep experimental trypanosomiasis. " 01/01/1988 - "brucei brucei, Cis-Pt (II) pentamidine was evaluated on an experimental sheep trypanosomiasis model, standardized by the Institute of Neurological Epidemiology and Tropical Neurology of Limoges (France). " 01/01/1988 - "[Antiparasitic activity of Cis-Pt (II) pentamidine in experimental trypanosomiasis of sheep caused by Trypanosoma brucei brucei]."
2.	Cutaneous Leishmaniasis 01/01/1990 - "A model of cis-Pt(II) pentamidine metabolism had been studied: this product could be used as a chemoprophylactic medicine against African trypanosomiasis and American leishmaniasis."
3.	African Trypanosomiasis (Nagana) 01/01/1990 - "A model of cis-Pt(II) pentamidine metabolism had been studied: this product could be used as a chemoprophylactic medicine against African trypanosomiasis and American leishmaniasis."
4.	Body Weight (Weight, Body) 01/01/1988 - "Cis-Pt (II) pentamidine was able to cure infected mice, without relapse, after a single subcutaneous injection of 12.5 mg.kg-1 body weight. "

Related Drugs and Biologics

1.	Antiparasitic Agents (Antiparasitics)

Related Therapies and Procedures

1.	Subcutaneous Injections