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chlorovulone I
coral prostanoid form Clavularia viridis; see also record for clavulones
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins A: 1719
chlorovulone I: 2
Biological Factors: 2472
Inflammation Mediators: 1113
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins A: 1719
chlorovulone I: 2
Related Diseases
1.
Sarcoma 180
09/01/1988 - "
Daily treatment with lipo-chlorovulone I (1.6 mg/kg/day, i.p.) and lipo-clavulone II (12.5 mg/kg/day, i.p.) on days 1 through 5 markedly prolonged the survival time (135% ILS and 73% ILS, respectively) of mice inoculated with sarcoma 180 as compared with that of a corresponding dose of respective free chlorovulone I and clavulone II. These results suggest that lipid microspheres may be used as drug delivery carriers for antitumor coral prostanoids in vivo.
"
2.
Leukemia
10/01/1987 - "
Bivariate DNA/bromodeoxyuridine analysis with a flow cytometer showed that chlorovulone I transiently arrested the cell cycle progression from G1 to S after 24-hr exposure to the nontoxic concentrations (0.03 and 0.09 microM) and caused the lasting blockade of leukemia cells in G1 at the cytotoxic concentration.
"
Related Drugs and Biologics
1.
Prostaglandins
2.
Lipids
3.
DNA (Deoxyribonucleic Acid)
4.
Bromodeoxyuridine (BrdU)
5.
clavulone II
Related Therapies and Procedures
1.
Microspheres (Microsphere)