fibrinogen Nijmegen

congenital dysfibrinogenemia associated with impaired t-PA mediated plasminogen activation & decreased binding of t-PA; Cys replaces Arg at position 44 of Bbeta polypeptide chain

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Biswas, A: 1 article (01/2015)
2.	Griesmacher, A: 1 article (01/2015)
3.	Hohenstein, K: 1 article (01/2015)
4.	Ivaškevičius, V: 1 article (01/2015)
5.	Oldenburg, J: 1 article (01/2015)
6.	Weigel, G: 1 article (01/2015)
7.	Würtinger, P: 1 article (01/2015)
8.	Zehetbauer, S: 1 article (01/2015)

Related Diseases

1.	Thrombosis (Thrombus) 01/01/2015 - "Fibrinogen Nijmegen, a mutation at the same position, is causative for thrombosis, whereas fibrinogen Innsbruck appears to lead to a bleeding tendency, illustrating that even mutations at the same position can cause contrary symptoms. "
2.	Hemorrhage 01/01/2015 - "Fibrinogen Nijmegen, a mutation at the same position, is causative for thrombosis, whereas fibrinogen Innsbruck appears to lead to a bleeding tendency, illustrating that even mutations at the same position can cause contrary symptoms. "
3.	Congenital Dysfibrinogenemia 08/30/1988 - "Fibrinogen Nijmegen: congenital dysfibrinogenemia associated with impaired t-PA mediated plasminogen activation and decreased binding of t-PA."

Related Drugs and Biologics

1.	Plasminogen
2.	Fibrinogen (Factor I)