prepro-thyrotropin-releasing hormone (178-199)

pro-TRH-connecting peptide; amino acid sequence given in first source

Also Known As:

prepro-TRH (178-199); preprothyrotropin-releasing hormone (178-199)

Networked: 2 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Protein Precursors: 37
    - prepro-thyrotropin-releasing hormone (178-199): 2
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Thyrotropin-Releasing Hormone: 1449
        prepro-thyrotropin-releasing hormone (178-199): 2
      - Hypothalamic Hormones: 68
        Pituitary Hormone-Releasing Hormones: 39
        Thyrotropin-Releasing Hormone: 1449
        prepro-thyrotropin-releasing hormone (178-199): 2
- Peptides: 82426
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Thyrotropin-Releasing Hormone: 1449
        prepro-thyrotropin-releasing hormone (178-199): 2

Experts

1.	Borlongan, Cesario V: 1 article (03/2002)
2.	Redei, Eva: 1 article (03/2002)
3.	Stahl, Christine E: 1 article (03/2002)
4.	Wang, Yun: 1 article (03/2002)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 11/26/1999 - "Prepro-thyrotropin-releasing hormone 178-199 exerts partial protection against cerebral ischemia in adult rats." 11/26/1999 - "The present observation provides the first evidence that prepro-TRH 178-199 can promote neuroprotection against cerebral ischemia." 11/26/1999 - "We examined in the present study the effects of the centrally administered prepro-thyrotropin-releasing-hormone 178-199 (prepro-TRH 178-199) on cerebral ischemia induced by ligation of the middle cerebral artery (MCA) in adult Sprague-Dawley rats. "
2.	Separation Anxiety (Separation Anxiety Disorder) 03/15/2002 - "Behavioral, hormonal and histological stress markers of anxiety-separation in postnatal rats are reduced by prepro-thyrotropin-releasing hormone 178-199." 03/15/2002 - "We investigated in the present study whether systemic injections of prepro-thyrotropin-releasing-hormone 178-199 (PPTRH 178-199) in postnatal 3-days old rat pups can provide ameliorative effects in a model of anxiety-separation disorder. "
3.	Infarction (Infarctions) 11/26/1999 - "In contrast, ischemic animals that received 6 microg/kg prepro-TRH 178-199 demonstrated infarction that did not differ in size and extent from those that received saline. " 11/26/1999 - "Interestingly, triphenyltetrazolium chloride staining (a marker for tissue metabolic activity) revealed that four of five ischemic animals that received 200 microg/kg prepro-TRH 178-199 showed a marked reduction (90-100%) in the infarction of the frontal cortex, although the posterior sections of the cortex remained infarcted. "

Related Drugs and Biologics

1.	triphenyltetrazolium

Related Therapies and Procedures

1.	Ligation
2.	Injections