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bis(perfluorobutyl)ethene

Also Known As:
(E)-isomer of bis(perfluorobutyl)ethene; (Z)-isomer of bis(perfluorobutyl)ethene; 1,2-bis(perfluorobutyl)ethylene; F-44E; F44E; bis(F-butyl)ethene; bis-PFBE; bis-perfluorobutylethene; bis-perfluorobutylethylene; therox; 5-Decene, 1,1,1,2,2,3,3,4,4,7,7,8,8,9,9,10,10,10-octadecafluoro-
Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
05/15/1989 - "This was true whether administered as a 48% (v/v) emulsion in 0.1 ml or as a 16% (v/v) emulsion in 0.3 ml. When the injection volume was varied from 0.1 ml to 0.4 ml at the 4 g/kg or 6 g/kg dose, thereby varying the emulsion concentration from 48% (v/v) to 12% (v/v) or 18% (v/v), the results tended to indicate that the volume of injection may be more important than the emulsion concentration, i.e., an injection volume of 0.2 ml produced the greatest tumor growth delay for both doses, and the emulsion concentration of 0.2 ml and 4 g/kg of F44E is 24% (v/v) whereas the emulsion concentration of 0.2 ml and 6 g/kg of F44E is 36% (v/v). "
05/15/1989 - "The enhancement in tumor growth delay with single dose radiation therapy increased as the dose of F44E was increased from 1.2 g/kg (0.03 ml) to 4 g/kg (0.1 ml). "
05/15/1989 - "However, when the F44E emulsion was administered every day with fractionated radiation and carbogen breathing, there was a marked enhancement in tumor growth delay observed across the entire dosage range, from 1.2 g/kg to 12 g/kg.(ABSTRACT TRUNCATED AT 400 WORDS)"
05/15/1989 - "When F44E was administered on treatment Days 1, 3, and 5 with carbogen breathing, there was an increased effect on tumor growth delay which reached a maximum at 4 g/kg (0.1 ml) of 10.0 +/- 1.2 days compared with 6.7 +/- 1.0 days for radiation with daily carbogen breathing. "
05/15/1989 - "We have examined the effects of a wide range of levels of Therox, a perfluorochemical emulsion containing bis-perfluorobutyl ethylene (F44E) with carbogen breathing on the tumor growth delay of the Lewis lung carcinoma produced by single dose radiation and fractionated radiation. "
2. Lewis Lung Carcinoma
3. Thrombosis (Thrombus)

Related Drugs and Biologics

1. bis(perfluorobutyl)ethene
2. carbogen
3. GTP-Binding Proteins (G-Protein)
4. Oxygen
5. Hemoglobins (Hemoglobin)
6. Emulsions
7. ethylene
8. Fluosol-DA