HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
6- methoxy- 8- (3- diethylaminopropylamino)quinoline
RN given refers to parent cpd
Also Known As:
6-methoxy-8-(3-diethylaminopropylamino)quinoline hydroiodide; plasmocid; 1,3-Propanediamine, N1,N1-diethyl-N3-(6-methoxy-8-quinolinyl)-
Networked:
15
relevant articles (
0
outcomes,
3
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolines: 146
Aminoquinolines: 29
6-methoxy-8-(3-diethylaminopropylamino)quinoline: 15
Experts
1.
Berman, Jonathan
: 1 article (11/2018)
2.
Brown, Tracey
: 1 article (11/2018)
3.
Dow, Geoffrey
: 1 article (11/2018)
4.
Toovey, Stephen
: 1 article (11/2018)
Related Diseases
1.
Necrosis
07/01/1967 - "
Studies on the pathogenesis of muscle necrosis in plasmocid intoxication.
"
04/24/1984 - "
A single injection of 5 mg/ml plasmocid produced massive fiber necrosis with extensive phagocytosis.
"
04/24/1984 - "
Two-step mechanism of myofibrillar protein degradation in acute plasmocid-induced muscle necrosis.
"
04/24/1984 - "
Acute muscle necrosis was induced in rats by intramuscular injection of plasmocid, a known myotoxic agent.
"
02/01/1967 - "
Taurine and creatine excretion after x-irradiation and plasmocid-induced muscle necrosis in the rat.
"
2.
Mitochondrial Diseases (Mitochondrial Disease)
08/01/1988 - "
This study was designed to clarify the role of phospholipase in the mechanism of plasmocid-induced mitochondrial dysfunction in the rat heart.
"
08/01/1988 - "
Administration of plasmocid also caused mitochondrial dysfunction, while no significant changes were observed in the lysosomal enzyme activity of either group.
"
08/01/1988 - "
The role of phospholipase in plasmocid-induced mitochondrial dysfunction in rat hearts.
"
08/01/1988 - "
These results suggested that plasmocid-induced mitochondrial dysfunction is based on the degrading of phospholipids by membrane bound phospholipase, and that lysosomal enzymes are unlikely to be involved in plasmocid-induced mitochondrial dysfunction.
"
3.
Brain Diseases (Brain Disorder)
07/01/1973 - "
Plasmocid encephalopathy in the rhesus monkey: a study of selective vulnerability.
"
4.
Muscular Diseases (Myopathy)
07/01/1985 - "
[Z-line alteration in plasmocid-induced myopathy].
"
12/01/1968 - "
Early biochemical changes in plasmocid myopathy.
"
03/01/1968 - "
The relation between twitch tension and action potential in plasmocid myopathy in the rat.
"
06/01/1987 - "
Abnormal increases of cathepsins L and B were seen even in the early stage of plasmocid myopathy and in a 20-day-old young mdx mouse before infiltration of macrophages, suggesting that autodigestion by intramyofibral lysosomal proteinases is an important event before digestion of the necrotic fibers by macrophage proteinases.
"
06/01/1987 - "
Skeletal muscles obtained from myopathies with myofiber necrosis, including mdx dystrophic mice, plasmocid-induced myopathy in rats, and patients with Duchenne muscular dystrophy, were examined immunohistochemically with anticathepsin-peroxidase conjugates.
"
5.
Poisoning
03/01/1968 - "
[Protracted nystagmus due to plasmocid poisoning].
"
11/01/1950 - "
II. The distribution of lesions caused by azide, malononitrile, plasmocid and dinitrophenol poisoning in rats.
"
Related Drugs and Biologics
1.
Phospholipases (Phospholipase)
2.
Quinacrine (Mepacrine)
3.
Proguanil (Paludrine)
4.
pentaquine
5.
Taurine
6.
Phospholipids (Phosphatides)
7.
Peptide Hydrolases (Proteases)
8.
Peroxidase (Myeloperoxidase)
9.
Enzymes
10.
Creatine
Related Therapies and Procedures
1.
Therapeutics
2.
Intraperitoneal Injections
3.
Intramuscular Injections