BRL 37344

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8 relevant articles (1 outcomes, 1 trials/studies) found for this Bio-Agent

Description: SB 206606 is the (R,R)-isomer

Also Known As:

(4-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)propyl)phenoxy)acetic acid; BRL 37344, (R*,R*)-(+-)-isomer; BRL 37344A; BRL-37344; SB 206606; SB-206606

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 40

Related Diseases

1.	Burns 08/01/1999 - "Maximal lipolytic responses to a specific beta(3)-AR agonist, BRL-37344, were significantly attenuated at post burn days (PBD) 3 and 7. Despite significant reduction of the cell surface beta(3)-AR number and its mRNA at PBD 3 and 7, BRL-37344 and forskolin-stimulated cAMP levels were not decreased" Get all the results and reference details, order at left...
2.	Fever (Fevers) 07/01/1999 - "The stress-induced fever was mimicked by central nervous system administration of the selective beta2-agonist, salbutamol, and the beta3-agonist, BRL 37344" 07/01/1999 - "The purpose of this study was to determine the relative contribution of the different beta-receptor types to stress fever using beta1-, beta2-, and beta3-receptor subtype selective antagonists (atenolol [beta1], ICI-118551 [beta2], and SR 59230A [beta3]) and agonists (dobutamine [beta1], salbutamol [beta2], and BRL 37344 [beta3]) on the Tb of rats" Get all the results and reference details, order at left...
3.	Stroke (Strokes) 12/01/2006 - "The analysis of the percentage of stroke work (SW) variations, in terms of EC(50) values, induced by BRL(37344) alone (10 nmol l(-1)), and in presence of SR(59230) (10 nmol l(-1)), indicated a competitive antagonism of SR(59230)" Get all the results and reference details, order at left...
4.	Tachycardia (Tachyarrhythmias) 02/01/1996 - "4. In vivo, the inhibition of colonic motility and the thermogenic response of brown adipose tissue elicited in rats by the selective beta 3-adrenoceptor agonists SR 58611A and BRL 37344 respectively were substantially diminished by the representative APAT, SR 59230A, at oral doses (< or = 5 mg kg-1) well below those half maximally effective (ID50) for preventing beta 1-(isoprenaline tachycardia > or = 80 mg kg-1) or beta 2-(salbutamol bronchodilatation, 44 mg kg-1) mediated responses" Get all the results and reference details, order at left...
5.	Pre-Eclampsia (Preeclampsia) 05/01/2007 - "Umbilical arteries from subjects with pre-eclampsia showed a weaker beta(2)- and beta(3)-receptor-mediated relaxation to formoterol and BRL 37344, suggesting that the reduced action of formoterol and BRL 37344 may be partly due to a decreased effect of cAMP." 05/01/2007 - "E(max) values of formoterol and BRL 37344 (for normotensive pregnant women: 87.33+/-0.87 and 53.25+/-1.17 vs. for pre-eclampsia: 73.68+/-1.58 and 43.64+/-1.19, n=12, P>0.05, respectively) were significantly smaller in strips from pre-eclamptic women (P<0.05), with no significant change in pD(2) values" Get all the results and reference details, order at left...
9 Diseases and 8 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Forskolin
3.	Albuterol (Salbutamol)
4.	SR 59230A
5.	Dobutamine
6.	Atenolol (Tenormin)
7.	ICI 118551
8.	Isoproterenol (Isoprenaline)
9.	NG-Nitroarginine Methyl Ester (L-NAME)
10.	beta Adrenergic Receptors
15 Drugs and Important Bio-Agents and 7 more articles analyzed in the Research Interface, order at left...

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