5- hydroxy- 6- (2- keto- 3- thiopropionyl)- 7,9,11,14- eicosatetraenoic acid

from transamination of leukotriene E4 by cysteine conjugate aminotransferase

Also Known As:

LTG(4); LTG4

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Arachidonic Acids: 122
        Leukotrienes: 4095
        5-hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid: 4
    - Essential Fatty Acids: 734
      - Arachidonic Acids: 122
        Leukotrienes: 4095
        5-hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid: 4
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Leukotrienes: 4095
        5-hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid: 4

Experts

1.	Ashihara, E: 1 article (06/2001)
2.	Hatsuse, M: 1 article (06/2001)
3.	Hirai, H: 1 article (06/2001)
4.	Inaba, T: 1 article (06/2001)
5.	Nakagawa, M: 1 article (06/2001)
6.	Nakahara, K: 1 article (06/2001)
7.	Okamoto, A: 1 article (06/2001)
8.	Okano, A: 1 article (06/2001)
9.	Sakatani, T: 1 article (06/2001)
10.	Shimazaki, C: 1 article (06/2001)

Related Diseases

1.	Leukemia 05/15/1994 - "The MLL gene involved in 11q23 translocations found in the majority of infantile leukemias and some secondary leukemias makes fusion transcripts with genes such as LTG4 (chromosome 4), LTG9 (chromosome 9), and LTG19 (chromosome 19) as a result of reciprocal translocation. " 04/01/1994 - "On the other hand, the MLL gene, associated with infant leukemia, acute monocytic leukemia and secondary leukemia, produces chimeric mRNAs between LTG4, 9, and 19 genes as well as the BCR-ABL chimeric gene in chronic myelogenous leukemia. "
2.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/01/1996 - "In this report, an infantile acute lymphoblastic leukemia with t(4;11) (q21; q23) was analyzed after each treatment for the presence of MRD by RT-PCR amplification of the MLL/LTG4 fusion gene which became available recently. "
3.	Residual Neoplasm 06/01/2001 - "Reverse transcriptase-polymerase chain reaction (RT-PCR) used to detect MLL/LTG4 chimeric mRNA showed no minimal residual disease (MRD) in the graft or bone marrow at the transplantation. "
4.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 04/01/1994 - "On the other hand, the MLL gene, associated with infant leukemia, acute monocytic leukemia and secondary leukemia, produces chimeric mRNAs between LTG4, 9, and 19 genes as well as the BCR-ABL chimeric gene in chronic myelogenous leukemia. "
5.	Acute Monocytic Leukemia (Acute Monoblastic Leukemia) 04/01/1994 - "On the other hand, the MLL gene, associated with infant leukemia, acute monocytic leukemia and secondary leukemia, produces chimeric mRNAs between LTG4, 9, and 19 genes as well as the BCR-ABL chimeric gene in chronic myelogenous leukemia. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	RNA-Directed DNA Polymerase (Reverse Transcriptase)

Related Therapies and Procedures

1.	Transplantation