deoxyaconitine

diterpene alkaloid from Aconitum karakolicum Rap.

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Cardiotoxicity 02/10/2023 - "Hezi inhibits Tiebangchui-induced cardiotoxicity and preserves its anti-rheumatoid arthritis effects by regulating the pharmacokinetics of aconitine and deoxyaconitine."
2.	B-Cell Lymphoma (Lymphoma, B Cell) 05/01/2022 - "The data of Aconiti Lateralis Radix Praeparata compounds in TCMSP database were collected, and after prediction and screening by the constructed high-throughput screening machine learning model, deoxyaconitine and benzoylmesaconine were selected to measure mitochondrial membrane potential, reactive oxygen species(ROS) level and protein expression of B-cell lymphoma 2(Bcl-2), Bcl-2-associated X protein(Bax) and peroxisome proliferator-activated receptor-γ-coactivator 1α(PGC-1α). "
3.	Paresis (Hemiparesis) 01/01/2003 - "In the combination B group, deoxyaconitine extended the time of sensory loss by 80%, the time of loss of weight-bearing by 50%, and that of flaccid paresis by 60% compared with the combination A group. "
4.	Rheumatoid Arthritis 02/10/2023 - "Hezi inhibits Tiebangchui-induced cardiotoxicity and preserves its anti-rheumatoid arthritis effects by regulating the pharmacokinetics of aconitine and deoxyaconitine."

1.	bcl-2-Associated X Protein (bcl 2 Associated X Protein)
2.	Peroxisome Proliferator-Activated Receptors (PPAR)
3.	Reactive Oxygen Species (Oxygen Radicals)
4.	Proteins (Proteins, Gene)
5.	Aconitine
6.	benzoylmesaconine