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ferrous histidinate

promoter of lipid peroxidation

Also Known As:

Fe(II)-histidinate

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Histidine: 2980
      - ferrous histidinate: 3
  - Cyclic Amino Acids: 3
    - Histidine: 2980
      - ferrous histidinate: 3
Organic Chemicals: 133
- Organometallic Compounds: 64
  - ferrous histidinate: 3

Related Diseases

1.	Neoplasms (Cancer) 12/06/1984 - "The combined application of Fe(II)-histidinate and vitamin C may offer a means to study lipid peroxidation of Ehrlich tumor cells in a controlled manner." 09/02/1988 - "In the absence of EAT cells, Fe(II)-histidinate was readily oxidized to Fe(III)-histidinate by oxygen, but this reaction was strongly retarded by the tumor cells. "
2.	Ehrlich Tumor Carcinoma 09/02/1988 - "The kinetics of the uptake of Fe(II)-histidinate, a known promoter of lipid peroxidation, into Ehrlich ascites tumor (EAT) cells and the intracellular binding of iron were studied in vitro. " 01/01/1989 - "After incubation of Ehrlich ascites tumor cells at 37 degrees C for 30 min with increasing concentrations of Fe(II) histidinate (Fe/His) the following parameters were determined: the formation of lipid hydroperoxides was measured fluorimetrically after reaction with dichlorofluorescein; 4-hydroxynonenal was determined by reversed-phase high-pressure chromatography after derivatization with dinitrophenylhydrazine; as a third parameter of lipid peroxidation the formation of 2-thiobarbituric-acid-reactive substances was determined. "

Related Drugs and Biologics

1.	Ascorbic Acid (Vitamin C)
2.	Oxygen (Dioxygen)
3.	Lipids
4.	Iron
5.	dinitrophenylhydrazine
6.	4-hydroxy-2-nonenal (4-hydroxynonenal)