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1-(4,6-propyl)dihydroalprenolol
Also Known As:
3H-DHA
Networked:
8
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Amino Alcohols: 20
Propanolamines: 4
Phenoxypropanolamines: 1
Alprenolol: 173
Dihydroalprenolol: 41
1-(4,6-propyl)dihydroalprenolol: 8
Alcohols: 595
Amino Alcohols: 20
Propanolamines: 4
Phenoxypropanolamines: 1
Alprenolol: 173
Dihydroalprenolol: 41
1-(4,6-propyl)dihydroalprenolol: 8
Propanols: 3
Propanolamines: 4
Phenoxypropanolamines: 1
Alprenolol: 173
Dihydroalprenolol: 41
1-(4,6-propyl)dihydroalprenolol: 8
Related Diseases
1.
Sleep Deprivation
07/25/1980 - "
After 72 or REM sleep deprivation there was a significant reduction in the Bmax for 3H-IMI and 3H-DHA binding with a concomitant increase in the apparent affinities.
"
07/25/1980 - "
Both the Kd and Bmax values for 3H-IMI and 3H-DHA binding remained unaffected after 24 or 48 h of REM sleep deprivation.
"
2.
Neoplasms (Cancer)
03/01/1991 - "
High number of 3H-DHA binding sites was distinctly decreased and 3H-QNB--was increased in lung malignant tumors as compared with normal tissue.
"
05/01/1991 - "
Amount of binding sites of 3H-QNB was significantly increased in cancer (Bmax = 377.5 +/- 65.5 fmole/mg) and did not change in chronic pneumonia (Bmax = 97.7 +/- 14.7 fmole/mg) as compared with normal tissues (Bmax = 108.9 +/- 12.1 fmole/mg); a number of binding sites of 3H-DHA was significantly decreased both in lung parenchyma under conditions of cancer (Bmax = 84.1 +/- 14.5 fmole/mg) and chronic pneumonia (Bmax = 113.8 +/- 10.3 fmole/mg) as compared with normal tissue (Bmax = 456.7 +/- 73.7 fmole/mg).
"
3.
Sarcoma 37
11/01/1985 - "
The sites of specific binding of 3H-L-dihydroalprenolol (3H-DHA) were identified on the surface of ascites sarcoma 37 cells, using competitive displacement and binding of the beta-adrenergic antagonists, 3H-DHA and L-propranolol.
"
4.
Pneumonia (Pneumonitis)
05/01/1991 - "
Amount of binding sites of 3H-QNB was significantly increased in cancer (Bmax = 377.5 +/- 65.5 fmole/mg) and did not change in chronic pneumonia (Bmax = 97.7 +/- 14.7 fmole/mg) as compared with normal tissues (Bmax = 108.9 +/- 12.1 fmole/mg); a number of binding sites of 3H-DHA was significantly decreased both in lung parenchyma under conditions of cancer (Bmax = 84.1 +/- 14.5 fmole/mg) and chronic pneumonia (Bmax = 113.8 +/- 10.3 fmole/mg) as compared with normal tissue (Bmax = 456.7 +/- 73.7 fmole/mg).
"
5.
Hypersensitivity (Allergy)
01/01/1987 - "
Receptor-binding assays were performed to evaluate the changes of beta- and alpha 1-adrenergic and muscarinic receptors in the nasal mucosa of subjects with nasal allergy and in guinea pigs sensitized with ovalbumin using radioligands 3H-DHA, 3H-prazosin and 3H-QNB, respectively.
"
Related Drugs and Biologics
1.
Propranolol (Inderal)
2.
Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
3.
Ovalbumin
4.
Lidocaine (Xylocaine)
5.
Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)
Related Therapies and Procedures
1.
Resuscitation