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4-amino-4,6-dideoxy-D-mannose
structure given in first source; RN refers to (D)-isomer
Also Known As:
4-amino-4,6-dideoxy-D-mannose, (L)-isomer; 4-amino-4,6-dideoxymannose; perosamine
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Sugars: 11126
Monosaccharides: 889
Hexoses: 549
Mannose: 1927
4-amino-4,6-dideoxy-D-mannose: 4
Experts
1.
Cook, Paul D
: 2 articles (10/2008 - 03/2008)
2.
Holden, Hazel M
: 2 articles (10/2008 - 03/2008)
3.
Carney, Amanda E
: 1 article (10/2008)
Related Diseases
1.
Dehydration (Water Stress)
10/07/2008 - "
Taken together, these studies shed light on why GDP-perosamine synthase functions as an aminotransferase whereas another very similar PLP-dependent enzyme, GDP-4-keto-6-deoxy- d-mannose 3-dehydratase or ColD, catalyzes a dehydration reaction using the same substrate.
"
2.
Infections
09/01/1991 - "
Infection with RB51 resulted in the production of significant levels of IgG type antibodies specific for B abortus cellular antigens distinct from the perosamine O-chain.
"
3.
Hemolysis
01/01/1992 - "
Serological cross-reaction of intact as well as chemically modified LPS from O1 Vibrio cholerae 569B (Inaba) with non-O1 V. cholerae Hakata LPS, which contain alpha(1-->2)-linked N-acetyl perosamine-homopolymer constituting their O polysaccharide chain, was studied by passive hemolysis test by using their LPS as antigen for sensitizing sheep red blood cells (SRBC).
"
4.
Foodborne Diseases
03/04/2008 - "
Perosamine or 4-amino-4,6-dideoxy- d-mannose is an unusual sugar found in the O-antigens of some Gram-negative bacteria such as Vibrio cholerae O1 (the causative agent of cholera) or Escherichia coli O157:H7 (the leading cause of food-borne illnesses).
"
5.
Cholera
03/04/2008 - "
Perosamine or 4-amino-4,6-dideoxy- d-mannose is an unusual sugar found in the O-antigens of some Gram-negative bacteria such as Vibrio cholerae O1 (the causative agent of cholera) or Escherichia coli O157:H7 (the leading cause of food-borne illnesses).
"
Related Drugs and Biologics
1.
Mannose (D-Mannose)
2.
Guanosine Diphosphate (GDP)
3.
Enzymes
4.
Transaminases (Aminotransferases)
5.
Antigens
6.
O Antigens (O Antigen)
7.
Polysaccharides (Glycans)
8.
Immunoglobulin G (IgG)
9.
Antibodies
10.
Sugars