fumonisin B2

produced by Fusarium moniliforme MRC 826; structure given in first source; has cancer-promoting ability

Also Known As:

fumonisin-B2; 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-9,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Fumonisins: 334
        fumonisin B2: 3
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Fumonisins: 334
      - fumonisin B2: 3

Related Diseases

1.	Allergic Contact Dermatitis 10/01/2023 - "We initially examined the immunotoxic potential of short-term, oral administration of fumonisin B1 (FB1, 1 mg/kg) and fumonisin B2 (FB2, 1 mg/kg), both naturally occurring fumonisins, using a BALB/c mouse model of allergic contact dermatitis and Dermatophagoides farina-induced asthma. "
2.	Neoplasms (Cancer) 06/01/1993 - "A short-term rat liver cancer initiation/promotion model was used to monitor the cancer-initiating activity of the mycotoxins fumonisin B1 (FB1), fumonisin B2 (FB2) and fumonisin B3 (FB3) as well as the N-acetyl derivatives of FB1 and FB2, and their respective hydrolysis products the aminopolyols. "
3.	Liver Neoplasms (Liver Cancer) 06/01/1993 - "A short-term rat liver cancer initiation/promotion model was used to monitor the cancer-initiating activity of the mycotoxins fumonisin B1 (FB1), fumonisin B2 (FB2) and fumonisin B3 (FB3) as well as the N-acetyl derivatives of FB1 and FB2, and their respective hydrolysis products the aminopolyols. "
4.	Hypersensitivity (Allergy) 10/01/2023 - "Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associated lymphoid tissue."
5.	Body Weight (Weight, Body) 07/01/1995 - "Fumonisin B2 (FB2), a secondary metabolite of the fungus Fusarium moniliforme, was administered at a dose of 7.5 mg/kg body weight to male BD IX rats by ip injection or by gavage. "

Related Drugs and Biologics

1.	fumonisin B1
2.	Fumonisins
3.	Interleukin-10 (Interleukin 10)
4.	Mycotoxins
5.	fumonisin B3

Related Therapies and Procedures

1.	Oral Administration