lysyl aminopeptidase (aminopeptidase Y)

metal-dependent aminopeptidase; enzyme from Saccharomyces cerevisiae inhibited by Zn; preferentially hydrolyzes N-terminal leucine peptides; does not hydrolyze X-Pro type peptides

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Klionsky, Daniel J: 1 article (01/2019)
2.	Parzych, Katherine R: 1 article (01/2019)

Related Diseases

1.	Polyps 01/01/2019 - "Abbreviations: Ams1: α-mannosidase; Ape1: aminopeptidase I; Ape3: aminopeptidase Y; Ape4: aspartyl aminopeptidase; Atg: autophagy related; Cps1: carboxypeptidase S; CTNS: cystinosin, lysosomal cystine transporter; CTSA: cathepsin A; CTSD: cathepsin D; Cvt: cytoplasm-to-vacuole targeting; Dap2: dipeptidyl aminopeptidase B; GS-bimane: glutathione-S-bimane; GSH: glutathione; LDs: lipid droplets; MVB: multivesicular body; PAS: phagophore assembly site; Pep4: proteinase A; PolyP: polyphosphate; Prb1: proteinase B; Prc1: carboxypeptidase Y; V-ATPase: vacuolar-type proton-translocating ATPase; VTC: vacuolar transporter chaperone."
2.	Neoplasms (Cancer) 01/01/1984 - "The activities of an acid proteinase, of an alkaline proteinase, of a lysine aminopeptidase and of a proteinase B inhibitor were measured in benign and malignant tumors of the human uterus. "
3.	Leiomyoma (Uterine Fibroids) 01/01/1984 - "In leiomyomas of the uterus the activities of the alkaline proteinase, of the lysine aminopeptidase, and of the proteinase inhibitor were decreased compared to the normal myometrium. "

Related Drugs and Biologics

1.	yeast proteinase B (cerevisin)
2.	Cathepsin A
3.	Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)
4.	Vacuolar Proton-Translocating ATPases (V-Type ATPase)
5.	Polyphosphates
6.	Peptide Hydrolases (Proteases)
7.	Mannosidases
8.	Proton-Translocating ATPases (ATPase, H+)
9.	Glutathione (Reduced Glutathione)
10.	Cystine (L-Cystine)