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3-hydroxy-4'-nitro-2-naphthanilide chloroacetate
Also Known As:
naphthol AS-D
Networked:
11
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Naphthols: 64
3-hydroxy-4'-nitro-2-naphthanilide chloroacetate: 11
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Naphthols: 64
3-hydroxy-4'-nitro-2-naphthanilide chloroacetate: 11
Related Diseases
1.
Leukemia
01/01/1979 - "
The most important differential diagnoses are the acute myeloblastic and myelomonocytic leukemias (naphthol-AS-D-chloroacetatesterase) immature epithelial tumours (lymphoepithelioma), and reactive processes (e.g.
"
01/01/1970 - "
[Acute myelo-monocytic leukemia with atypical naphthol-AS-D-chloracetate esterase positive eosinophils].
"
05/01/1983 - "
[Use of naphthol-AS-D-chloroacetate esterase and naphthol-AS-D-acetate esterase stains in differentiating various types of acute leukemia].
"
07/01/1979 - "
Blood and bone-marrow smears from adult patients with acute leukemias were stained for esterase reaction, consecutively with naphthol AS D-chloracetate (chloracetate esterase) followed by alpha naphthyl butyrate (nonspecific esterase).
"
2.
Neoplasms (Cancer)
02/01/1989 - "
A reevaluation of the electron micrographs of the skin and lymph node lesion showed primary lysosomal granules within the tumor cell cytoplasm consistent with a diagnosis of leukemic infiltrates (granulocytic sarcoma); additionally, the naphthol AS-D chloracetate esterase activity of the skin lesion was positive, supporting the diagnosis of granulocytic sarcoma.
"
11/01/1993 - "
Enzyme-histochemically, the tumor cells and normal SSEC revealed naphthol AS-D acetate esterase activity but no reaction for ALPase, whereas normal vascular EC other than SSEC in the spleen were positive for the latter but negative for the former.
"
05/01/1977 - "
Cytochemical stains of formalin-fixed, paraffin-embedded tissues confirmed the granulocytic origin of the neoplasm: leukemic cells in skin biopsies, bone marrow aspirates, and autopsy specimens contained abundant naphthol AS-D chloracetate esterase.
"
3.
Histiocytoma
09/30/1965 - "
[On the determination of naphthol-AS-D-chloracetate-esterase in histiocytomas of the skin].
"
4.
Cutaneous Mastocytosis
01/01/1981 - "
[Occurrence of naphthol-AS-D-chloracetate-esterase-activity in mast cells with special references to cutaneous mastocytoses (author's transl)].
"
5.
Myeloid Sarcoma (Chloroma)
02/01/1989 - "
A reevaluation of the electron micrographs of the skin and lymph node lesion showed primary lysosomal granules within the tumor cell cytoplasm consistent with a diagnosis of leukemic infiltrates (granulocytic sarcoma); additionally, the naphthol AS-D chloracetate esterase activity of the skin lesion was positive, supporting the diagnosis of granulocytic sarcoma.
"
Related Drugs and Biologics
1.
Esterases
2.
Carboxylesterase (Hydrolase S)
3.
Naphthol AS D Esterase (ANAE)
4.
Acetylesterase
5.
Paraffin
6.
Formaldehyde (Formol)
7.
Enzymes
8.
alpha-naphthyl butyrate