imiquimod (Aldara)

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702 relevant articles (165 outcomes, 143 trials/studies) found for this Drug

Description: effective against herpes simplex virus infections in animals; structure given in first source

Also Known As:

Aldara; 1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine; 3M Brand of Imiquimod; R 837; R-837; S 26308; S-26308; 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 23

2-Ring Heterocyclic Compounds

Quinolines: 58

Aminoquinolines: 7

imiquimod: 702

Experts

1.	Berman, Brian: 8 articles (01/2008 - 05/2002)
2.	Stockfleth, E: 8 articles (12/2007 - 10/2000)
3.	Dummer, Reinhard: 8 articles (12/2007 - 01/2003)
4.	Owens, Mary: 8 articles (11/2006 - 09/2002)
5.	Urosevic, Mirjana: 6 articles (12/2007 - 01/2003)
6.	Peris, Ketty: 6 articles (11/2007 - 07/2003)
7.	Skinner, Robert B: 6 articles (03/2006 - 07/2002)
8.	Benninghoff, Bernd: 6 articles (01/2005 - 11/2002)
9.	Slade, H B: 5 articles (12/2007 - 07/2000)
10.	Micantonio, Tamara: 5 articles (11/2007 - 07/2003)

Related Diseases

1.	Warts (Wart) 12/01/2007 - "For a few years clinical studies focussed on the long-term efficacy of the immunomodulatory therapy (sustained clearance from warts) and most recent studies compared the efficacy of ablative, destructive and imiquimod monotherapy as well as combination therapies." 10/01/2002 - "Published studies indicate that imiquimod results in complete clearance of warts in more than 50% of patients" 01/01/2001 - "In three trials complete clearance of warts at the end of treatment plus no recurrence occurred in 37% of patients treated with imiquimod 5% cream and 4% of those treated with placebo" 01/01/2001 - "In five trials with HIV-negative patients complete clearance of warts at the end of treatment occurred in 51% of patients treated with imiquimod 2% or 5% cream and 6% of placebo treated patients" 08/01/1999 - "Preliminary results of a vehicle-controlled study showed that the rate of partial clearance of warts (defined as a reduction in baseline wart area of >50%) [38%] was significantly higher with imiquimod 5% cream than with vehicle cream; however, the rate of complete clearance was not significantly higher than with vehicle cream" Get all the results and reference details, order at left...
2.	Basal Cell Carcinoma (Rodent Ulcer) 01/01/2007 - "BACKGROUND: Imiquimod is a Toll-like receptor-7 agonist capable of inducing complete clearance of basal cell carcinoma (BCC) and other cutaneous malignancies" 09/01/2004 - "BACKGROUND: Imiquimod is a modifier of the immune response that has been proven to be an effective treatment for basal cell carcinoma (BCC)" 08/01/2005 - "We concluded that topical 5 per cent imiquimod is an effective treatment of various subtypes of basal cell carcinoma" 03/01/2005 - "BACKGROUND: Imiquimod is an immune response modifier shown to be effective in basal cell carcinoma (BCC)" 09/01/2004 - "Imiquimod is an immune-response modifier that has been shown to be effective in the treatment of superficial and nodular basal cell carcinoma (BCC)" Get all the results and reference details, order at left...
3.	Condylomata Acuminata (Genital Wart) 04/01/2001 - "When 5% imiquimod cream is applied three times a week up to 16 weeks, approximately two thirds of women treated with imiquimod achieve complete clearance of genital warts, whereas only about one third of men clear completely" 09/01/2000 - "CONCLUSION: The study demonstrated that 2% imiquimod in cream with mild non-objective side effects is safe, tolerable and significantly more effective than placebo in curing external genital warts in males." 07/01/1998 - "In conclusion, the data presented demonstrate that 2% imiquimod in cream with mild to moderate subjective side effects is significantly more effective than placebo in eliminating genital warts in women." 04/01/1998 - "Patient-applied 5% imiquimod cream is effective for the treatment of external genital warts and has a favorable safety profile." 02/01/2007 - "The first drug in this therapeutic class, Immiquimod (Aldara), has been shown to be effective in treating lesions induced by Human Papillomavirus (HPV) such as genital warts or cervical and vulvar dysplasia, by stimulating the immune system of an infected individual" Get all the results and reference details, order at left...
4.	Keratosis 06/01/2006 - "Complete clearance occurred in 50% of patients treated with imiquimod, compared to 5% treated with vehicle, and the number needed to treat (NNT) for one patient to have their keratosis completely cleared after 12-16 weeks was 2.2 (95% confidence interval 2.0-2.5)" 08/01/2007 - "CONCLUSION: Imiquimod 3x/wk in one or two courses of treatment appears to be effective for the treatment of actinic keratoses on the head, providing long-term clinical benefits" 08/01/2007 - "BACKGROUND: A shorter dosing regimen of imiquimod for the treatment of actinic keratosis may be effective, with long-term clinical benefits" 07/01/2007 - "BACKGROUND: Imiquimod has been investigated as a safe and effective therapeutic option for the treatment of actinic keratosis (AK)" 01/01/2006 - "BACKGROUND: Imiquimod 5% cream is a topically applied immune response modifier that has been shown to give effective treatment of actinic keratosis (AK)" Get all the results and reference details, order at left...
5.	Hutchinson's Melanotic Freckle (Lentigo Maligna) 10/01/2007 - "Imiquimod 5% cream appears effective in the treatment of lentigo maligna" 02/01/2005 - "Topical treatment with imiquimod seems to be effective and safe in lentigo maligna." 10/01/2000 - "Imiquimod: a novel treatment for lentigo maligna." 11/01/2003 - "To gauge the efficacy of this therapy, we undertook a trial of topical imiquimod in 30 subjects with histologically confirmed lentigo maligna" 04/01/2006 - "Usefulness of dermoscopy to monitor clinical efficacy of imiquimod treatment for lentigo maligna." Get all the results and reference details, order at left...
149 Diseases and 702 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	imiquimod (Aldara)
2.	Interferons
3.	Fluorouracil (Carac)
4.	Podophyllotoxin (Condylox)
5.	Cosmetics
6.	Cytokines
7.	Messenger RNA (mRNA)
8.	Proteins (Proteins, Gene)
9.	Diclofenac (SR 38)
10.	Argon
133 Drugs and Important Bio-Agents and 197 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Transplantation (Transplant Recipients)
2.	Curettage
3.	Aftercare (After-Treatment)
4.	Transplants (Transplant)
5.	Photochemotherapy (Photodynamic Therapy)
24 Therapies and Procedures and 91 more articles analyzed in the Research Interface, order at left...

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