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velnacrine

RN given refers to (+-)-isomer; RN for cpd without isomeric designation not available 8/88; structure in first source; potential Alzheimer's disease drug but trial halted due to abnormal liver tests
Also Known As:
1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate; 1,2,3,4-tetrahydro-9-aminoacridine-1-ol; 1-hydroxytacrine; 9-ATHCO; 9-amino-1,2,3,4-tetrahydroacridin-1-ol; HP 029; HP-029; velnacrine maleate
Networked: 22 relevant articles (4 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Silva-Herdade, A S: 1 article (01/2013)
2. Saldanha, C: 1 article (01/2013)
3. Wilcock, G G W: 1 article (01/2004)
4. Birks, J: 1 article (01/2004)
5. Cecchetti, V: 1 article (11/2001)
6. Fravolini, A: 1 article (11/2001)
7. Filipponi, E: 1 article (11/2001)
8. Temperini, A: 1 article (11/2001)
9. Tabarrini, O: 1 article (11/2001)
10. Lamperti, M G: 1 article (11/2001)

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Neurobehavioral Manifestations
3. Inflammation
4. Dementia (Dementias)
5. Hypersensitivity (Allergy)

Related Drugs and Biologics

1. Cholinesterases (Cholinesterase)
2. velnacrine
3. Tacrine (Cognex)
4. Acetylcholine (Acetylcholine Chloride)
5. Cytoskeletal Proteins
6. Carbon Monoxide
7. Aminacrine (Aminoacridine)
8. Acetylcholinesterase
9. maleic acid (maleate)
10. N-methylacridine