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2,4,5-trihydroxypentanoic acid gamma-lactone

Also Known As:

2,4,5-TP; 2-deoxy-ribono-1,4-lactone; 2-deoxyribonolactone

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - 2,4,5-trihydroxypentanoic acid gamma-lactone: 7
  - Acyclic Acids
    - Sugar Acids: 4
      - 2,4,5-trihydroxypentanoic acid gamma-lactone: 7
Carbohydrates: 22023
- Sugar Acids: 4
  - 2,4,5-trihydroxypentanoic acid gamma-lactone: 7

Experts

1.	Sandler, Dale P: 2 articles (06/2020 - 10/2013)
2.	Alavanja, Michael C: 1 article (06/2020)
3.	Beane Freeman, Laura E: 1 article (06/2020)
4.	Blair, Aaron: 1 article (06/2020)
5.	Engel, Lawrence S: 1 article (06/2020)
6.	Koutros, Stella: 1 article (06/2020)
7.	Lerro, Catherine C: 1 article (06/2020)
8.	Satagopan, Jaya: 1 article (06/2020)
9.	Werder, Emily J: 1 article (06/2020)
10.	Averill, April M: 1 article (01/2017)

Related Diseases

1.	Hypoglycemia (Reactive Hypoglycemia) 12/01/1990 - "Only the 2S,4S-isomer of 2,4,5-TP induced hypoglycemia with hyperinsulinemia, whereas opposite effects were produced by the 3S-isomer of 3,4-DB. " 02/01/1989 - "Potent hypoglycemia with hyperinsulinemia was caused by the 2S,4S-isomer of 2,4,5-TP, and the S-isomer of 3,4-DB caused responses that were reciprocal to those to 2,4,5-TP. " 11/08/1988 - "Hyperglycemia was induced by 2.50 mumol 3,4-DB leaving insulin unaffected; 2.50 mumol 2,4,5-TP caused hypoglycemia, with a persistent but not significant rise in insulin. "
2.	Hyperinsulinism (Hyperinsulinemia) 12/01/1990 - "Only the 2S,4S-isomer of 2,4,5-TP induced hypoglycemia with hyperinsulinemia, whereas opposite effects were produced by the 3S-isomer of 3,4-DB. " 02/01/1989 - "Potent hypoglycemia with hyperinsulinemia was caused by the 2S,4S-isomer of 2,4,5-TP, and the S-isomer of 3,4-DB caused responses that were reciprocal to those to 2,4,5-TP. "
3.	Neoplasms (Cancer) 01/01/2017 - "Because Pol θ expression correlates with poor cancer prognosis, the ability of Pol θ to bypass the C4'-oxidized abasic site (C4-AP) and 2-deoxyribonolactone (L), which are generated by cytotoxic agents, is of interest. "
4.	Kidney Neoplasms (Kidney Cancer) 10/15/2023 - "The seven constituents directly related to kidney cancer incidence (and corresponding standardized incidence ratios) were chlordane (1.06; 95% confidence interval [CI], 1.02-1.10), dieldrin (1.04; 95% CI, 1.01-1.07), 1,2-dichloropropane (1.04; 95% CI, 1.02-1.05), 2,4,5-TP (1.03; 95% CI, 1.01-1.05), glyphosate (1.02; 95% CI, 1.01-1.04), endothall (1.02; 95% CI, 1.01-1.03), and carbaryl (1.02; 95% CI, 1.01-1.03). "
5.	Hypothyroidism 10/01/2013 - "There was increased odds of hypothyroidism with ever use of the herbicides 2,4-D (2,4-dichlorophenoxyacetic acid), 2,4,5-T (2,4,5-trichlorophenoxyacetic acid), 2,4,5-TP (2,4,5-trichlorophenoxy-propionic acid), alachlor, dicamba, and petroleum oil. "

Related Drugs and Biologics

1.	2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T)
2.	2,4-Dichlorophenoxyacetic Acid (2,4 Dichlorophenoxyacetic Acid)
3.	Carbaryl (Sevin)
4.	Petroleum (Crude Oil)
5.	Insulin (Novolin)
6.	Herbicides
7.	Dieldrin
8.	Dicamba
9.	Cytotoxins (Cytolysins)
10.	Chlordan (Chlordane)