|1.||Whalen, Margaret M: 3 articles (10/2010 - 02/2002)|
|2.||Shang, Xianmei: 2 articles (04/2014 - 02/2012)|
|3.||Xiang, Guangya: 2 articles (04/2014 - 02/2012)|
|4.||Pellerito, C: 1 article (09/2015)|
|5.||Sabella, S: 1 article (09/2015)|
|6.||Ferrante, F: 1 article (09/2015)|
|7.||Notaro, A: 1 article (09/2015)|
|8.||Fiore, T: 1 article (09/2015)|
|9.||Morana, O: 1 article (09/2015)|
|10.||Calvaruso, G: 1 article (09/2015)|
10/01/2010 - "Previous studies have shown that dibutyltin (DBT) interferes with the function of human natural killer (NK) cells, diminishing their capacity to destroy tumor cells, in vitro. "
02/01/2012 - "Novel di-n-butyltin(IV) derivatives: Synthesis, high levels of cytotoxicity in tumor cells and the induction of apoptosis in KB cancer cells."
02/01/2002 - "Recently, we have demonstrated that the ability of NK cells to kill tumor cells is greatly diminished after a 1-h exposure to dibutyltin. "
10/30/2014 - "Preliminary in vitro cytotoxicity studies on five human tumor cells lines (HL-60, A549, HT-29, HCT-116 and Caco-2) by MTT assay reveal that di-n-butyltin(IV) complex 2 and diphenyltin(IV) complex 4 triggered significant antiproliferative effects in cultured tumor cells, and their cytotoxic activity correlates with intracellular organotin(IV) concentration. "
04/01/2007 - "This study investigates the role that decreased ATP levels may play in dibutyltin (DBT)-induced decreases in the tumor-cell-lysing (lytic) function of natural killer (NK) cells. "
01/01/1989 - "An immunohistochemical study of dibutyltin-induced thymus atrophy."
09/01/2009 - "The study reported here focused on cell death in the thymus as a contributing factor in the induction of thymic atrophy following exposure to dibutyltin (DBTC) and tributyltin (TBTC). "
01/01/1988 - "Dibutyltin and tributyltin compounds induce thymus atrophy in rats due to a selective action on thymic lymphoblasts."
01/01/1988 - "The log dose-effect relationships for both compounds were linear and ran parallel over a dose range of 5-60 mg/kg. Dose levels calculated to cause 50% reduction of relative thymus weight were 18 mg DBTC and 29 mg TBTC per kg body wt. A single oral dose of mono-n-butyltin trichloride (MBTC), however, did not cause thymus atrophy at dose levels up to 180 mg/kg. The kinetics of the dibutyltin- and tributyltin-induced thymus atrophy in rats were investigated by measuring thymus weight, total thymic cell count, number of small, intermediate and large cells and the incorporation of DNA, RNA and protein precursors into isolated thymocytes during a period of 9 days after a single oral dose. "
05/01/2013 - "The toxic effects of the organotin compounds (OTCs) monobutyltin (MBT), dibutyltin (DBT), and tributyltin (TBT) were evaluated in vitro in a neuroblastoma human cell line. "
05/01/2013 - "In vitro approaches to evaluate toxicity induced by organotin compounds tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) in neuroblastoma cells."
|3.||Adenosine Triphosphate (ATP)
|8.||RNA (Ribonucleic Acid)