sarasinoside A1

isolated from Palauan marine sponge Asteropus sarasinosum; structure given in first source

Also Known As:

sarasinoside-A1; Cholesta-8,24-dien-23-one, 3- ((O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1-4)-O-(O-beta-D-glucopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-6)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-2))-beta-D-xylopyranosyl-)oxy)-4,4-dimethyl-, (3beta,5alpha)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Andersen, Raymond J: 1 article (05/2013)
2.	Austin, Pamela: 1 article (05/2013)
3.	Freeman, Spencer A: 1 article (05/2013)
4.	Gold, Michael R: 1 article (05/2013)
5.	Gray, Christopher A: 1 article (05/2013)
6.	Roberge, Michel: 1 article (05/2013)
7.	Roskelley, Calvin D: 1 article (05/2013)
8.	Vogl, A Wayne: 1 article (05/2013)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2013 - "Therefore, our findings with sarasinoside A1 suggest that it may be possible to re-epithelialize metastatic tumor cells with phenotypic consequence even when E-cadherin is completely absent." 05/01/2013 - "The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner."
2.	Breast Neoplasms (Breast Cancer) 05/01/2013 - "We used mesenchymally transformed, E-cadherin-negative MDA-MB-231 breast carcinoma cells in a natural product screen and determined that the triterpenoid saponin sarasinoside A1 inhibited their invasion and the invasion of a number of other tumor cell lines. "

Related Drugs and Biologics

1.	Cadherins (E-Cadherin)
2.	Triterpenes
3.	Saponins