|1.||Bhatia, Madhav: 2 articles (05/2007 - 07/2006)|
|2.||Clément, Marie Véronique: 2 articles (05/2007 - 07/2006)|
|3.||Wallig, Matthew: 2 articles (05/2007 - 07/2006)|
|4.||Adhikari, Sharmila: 2 articles (05/2007 - 07/2006)|
|5.||Cao, Yang: 2 articles (05/2007 - 07/2006)|
|6.||Rácz, Akos: 1 article (12/2009)|
|7.||Wijsman, John A: 1 article (12/2009)|
|8.||Nicholson, Jeremy K: 1 article (12/2009)|
|9.||Keun, Hector C: 1 article (12/2009)|
|10.||Noszál, Béla: 1 article (12/2009)|
01/01/1998 - "This paper reviews the evidence for a cyanide connection, with reference to experimental studies using another plant nitrile, crambene; and then examines the hypothesis that chronic pancreatitis represents a manifestation of uncoordinated detoxification reactions between pancreatic cytochrome P450 mono-oxygenases and phase II conjugating enzymes, resulting in the irreversible consumption of glutathione in the acinar cell. "
05/01/2007 - "Thus, induction of pancreatic acinar cell apoptosis by crambene protects mice against acute pancreatitis via induction of anti-inflammatory pathways."
05/01/2007 - "Our previous work has demonstrated that induction of pancreatic acinar cell apoptosis by crambene protects mice against acute pancreatitis. "
05/01/2007 - "Induction of apoptosis by crambene protects mice against acute pancreatitis via anti-inflammatory pathways."
05/01/2007 - "IL-10 plays an important role in crambene-induced protection in acute pancreatitis. "
12/01/2009 - "The time-related metabolic effects of 1-cyano-2-hydroxy-3-butene (CHB, crambene), a naturally occurring nitrile and experimental model toxin causing exocrine pancreatitis, have been investigated in rats using high-resolution NMR spectroscopy of urine and serum in combination with pattern recognition analysis. "
07/01/1993 - "The in vitro responses of canine mammary tumor (CMT-13) cells and normal canine mammary (NCM) cells to 1-cyano-2-hydroxy-3-butene (CHB), a naturally occurring nitrile in cruciferous plants, and selenium (Se) were investigated. "
08/01/2001 - "1-Cyano-2-hydroxy-3-butene (crambene) is a nitrile found in cruciferous vegetables that causes significant upregulation of quinone reductase and glutathione S-transferases in vivo and in vitro, making it a likely candidate as a cancer chemopreventive compound. "
|5.||Hepatocellular Carcinoma (Hepatoma)
|1.||Glutathione (Reduced Glutathione)
|4.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|6.||Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
|8.||Interleukin-10 (Interleukin 10)
|9.||NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)