dichlobanil

05/02/2019 - "To analyze the potential effects that selected herbicides (MCPA, mesotrione, bifenox and dichlobenil) may have upon cancerous cells, we conducted studies of the cytotoxicity of physiological concentrations of four pesticides and the mix of TA with tested herbicides in three different breast cancer cell lines (MCF-7, ZR-75-1 and MDA-MB-231) and one normal healthy breast cell line MCF-12A. "

07/28/1993 - "Twenty-eight hours after a single dose (12 mg/kg) of dichlobenil, characteristic regions of the olfactory mucosa showed signs of necrosis in H&E stained sections. "
03/01/1997 - "Transmission electron microscopy showed vacuolations (1 hr) and necrosis (4 hr) in the Bowman's glands following intraperitoneal injection of dichlobenil (25 mg/kg) in C57B1 mice, whereas no lesions were noted in the olfactory neuroepithelium at these timepoints. "
04/01/2009 - "The herbicide dichlobenil selectively causes necrosis of the dorsomedial part of olfactory neuroepithelium (NE) with permanent damage to the underlying mucosa, whereas the lateral part of the olfactory region and the nasal respiratory mucosa remain undamaged. "
10/31/1997 - "Special attention is put on the herbicide dichlobenil which induces necrosis in the olfactory mucosa following a cytochrome-P450-mediated metabolic activation and covalent binding in the Bowman's glands."
03/01/1997 - "The herbicide dichlobenil (2,6-dichlorobenzonitrile) is a tissue-specific inducing necrosis in the olfactory mucosa. "

10/27/2019 - "The Analysis of Bifenox and Dichlobenil Toxicity in Selected Microorganisms and Human Cancer Cells."
01/01/1991 - "Dichlobenil induced a significant increase of malignant tumors (lymphoma, mesothelioma, hepatocellular carcinoma, and pulmonary alveologenic carcinoma) with respect to the controls (p less than 0.01 in both treated groups). "

03/01/2009 - "Balamuthia mandrillaris: staining properties of cysts and trophozoites and the effect of 2,6-dichlorobenzonitrile and calcofluor white on encystment."
08/01/2018 - "We used four types of amoebicidal agents including 0.02% PHMB, 0.02% chlorhexidine digluconate, 100 μM chloroquine, and 100 μM 2,6-dichlorobenzonitrile to kill Acanthamoeba trophozoites and cysts. "

02/01/1974 - "Chloracne induced by 2,6-dichlorobenzonitrile."