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norwogonin

Also Known As:

5,7,8-hydroxyflavone; 7,8,4'-trihydroxyflavone; isowogonin; nor-wogonin

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        norwogonin: 8
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        norwogonin: 8

Experts

1.	Gao, Rongmin: 1 article (01/2021)
2.	Jia, Zhengping: 1 article (01/2021)
3.	Jing, Linlin: 1 article (01/2021)
4.	Ma, Huiping: 1 article (01/2021)
5.	Shao, Jin: 1 article (01/2021)
6.	Zhang, Dongmei: 1 article (01/2021)
7.	Zhang, Jie: 1 article (01/2021)
8.	Chen, Changwang: 1 article (05/2020)
9.	Liu, Gao: 1 article (05/2020)
10.	Wang, Zhang: 1 article (05/2020)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 05/01/2020 - "The results showed that norwogonin causes substantial reduction in the viability of the human colorectal carcinoma cells in a dose-dependent manner, exhibiting an IC50 of 15.5 µM in cancer cells and IC50 of 90 µM in normal cell lines. " 05/01/2020 - "In conclusion, the current study shows that norwogonin has a potential to inhibit in vitro colorectal cancer cells growth by triggering apoptosis, autophagy and cell cycle arrest and as such could be developed as a possible anticancer agent."
2.	Infections 01/01/2013 - "Further studies are warranted to ascertain the prophylactic and therapeutic potential of norwogonin for infections due to multidrug-resistant A. "
3.	Triple Negative Breast Neoplasms 04/01/2019 - "Herein, we investigated the mechanisms of nor-wogonin actions in triple-negative breast cancer (TNBC) cells. " 04/01/2019 - "Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3."
4.	Respiratory Syncytial Virus Infections 08/10/2023 - "Finally, through the application of the gray correlation analysis method, we identified Baicalein, Baicalin, Oroxylin A 7-O-beta-d-glucuronide, Wogonoside, Norwogonin, and Wogonin as potential pharmacodynamic material bases of Scutellaria baicalensis Georgi against RSV infection."
5.	Virus Diseases (Viral Diseases) 09/01/2016 - "Norwogonin, oroxylin A, and mosloflavone also inhibited virus replication during the initial stage of virus infection, and they inhibited viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)
2.	Antioxidants
3.	wogonin
4.	5,7- dihydroxy- 6- methoxy- 2- phenylchromen- 4- one
5.	Capsid Proteins (Capsid Protein)
6.	Hydroxyl Radical
7.	Proteins (Proteins, Gene)
8.	Enzymes
9.	mosloflavone
10.	wogonoside