BRL 34778

structure given in first source; potent and specific dopamine D2 receptor antagonist

Also Known As:

4-amino-5-chloro-2-methoxy-N-(9-(fluorophenylmethyl)-9-azabicyclo(3.3.1)non-3-yl)benzamide; BRL-34778; Benzamide, 4-amino-5-chloro-N-(9-((4-fluorophenyl)methyl)-9-azabicyclo(3.3.1)non-3-yl)-2-methoxy-, exo-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Catalepsy 01/01/1988 - "In contrast to its high potency in models for antipsychotic activity, BRL 34778 is much weaker in models for extrapyramidal effects and sedation (4 h ED50s PO are 2.4 mg/kg for inducing catalepsy in rats and 1.14 mg/kg for inhibition of rearing behaviour in rats). "

Related Drugs and Biologics

1.	Antipsychotic Agents (Antipsychotics)