|1.||Wu, Ping: 3 articles (12/2014 - 01/2012)|
|2.||Li, Xia: 2 articles (12/2014 - 05/2014)|
|3.||Fung, Kwok-Pui: 2 articles (05/2014 - 01/2012)|
|4.||Zeng, Xue-li: 1 article (12/2014)|
|5.||Liu, Fei-yan: 1 article (12/2014)|
|6.||Sun, Jian-guo: 1 article (12/2014)|
|7.||Fung, Kwok Pui: 1 article (12/2014)|
|8.||Xiang, Jun: 1 article (12/2014)|
|9.||Li, Hua: 1 article (05/2014)|
|10.||Zeng, Xueli: 1 article (05/2014)|
05/01/2014 - "Taken together, our data demonstrated that clitocine is a potent Mcl-1 inhibitor that can effectively induce apoptosis to suppress drug-resistant human cancer cell growth both in vitro and in vivo, and thus holds great promise for further development as potentially a novel therapeutic agent to overcome drug resistance in cancer therapy."
05/01/2014 - "Clitocine treatment inhibited drug-resistant human cancer cell growth in vitro in a dose- and time-dependent manner. "
05/01/2014 - "Clitocine is a natural amino nucleoside isolated from mushroom and has been shown to inhibit cancer cell proliferation in vitro. "
05/01/2014 - "Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo."
04/18/2008 - "Here, for the first time, we studied the molecular mechanism of clitocine-induced apoptosis in human cervical cancer cells (HeLa). "
|2.||Colonic Neoplasms (Colon Cancer)
12/28/2014 - "At the present study, we observed that clitocine can induce apoptosis in six tested human colon cancer cell lines accompanied by suppression of Mcl-1. "
12/28/2014 - "Collectively, our studies suggest clitocine can induce apoptosis and potentiate ABT-737 lethality in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak to trigger apoptosis. "
12/28/2014 - "At the molecular level we determined Mcl-1 is the potential target through which clitocine can sensitize human colon cancer cells to ABT-737 induced apoptosis. "
12/28/2014 - "Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak."
|3.||Hepatocellular Carcinoma (Hepatoma)
|2.||Cytochromes c (Cytochrome c)
|1.||Heterologous Transplantation (Xenotransplantation)