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muristerone A

a phytoecdysteroid

Also Known As:

2 beta,3 beta,5 beta,11 alpha,14 alpha,20R,22R-heptahydro xycholest-7-en-6-one; muristerone

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Cholestenes
        Cholestenones
        Ecdysteroids: 92
        Ecdysterone: 109
        muristerone A: 5
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Invertebrate Hormones: 1
    - Insect Hormones: 4
      - Ecdysteroids: 92
        Ecdysterone: 109
        muristerone A: 5

Experts

1.	Hermiston, Terry W: 1 article (02/2008)
2.	Nair, Ayyappan: 1 article (02/2008)
3.	Xie, Jinger: 1 article (02/2008)
4.	Enenkel, Barbara: 1 article (09/2002)
5.	Fussenegger, Martin: 1 article (09/2002)
6.	Meents, Heiko: 1 article (09/2002)
7.	Werner, Rolf G: 1 article (09/2002)
8.	Charles, Ian G: 1 article (02/2002)
9.	Liu, Lizhi: 1 article (02/2002)
10.	Xu, Weiming: 1 article (02/2002)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 04/22/1999 - "In order to study the function of p21waf in a p53-deficient environment, we established an inducible expression of p21waf in the p53-null lung cancer cell line H1299, based on the muristerone-regulated system. "
2.	Neoplasms (Cancer) 02/01/2008 - "In contrast to both muristerone A and mifepristone that showed no significant toxicity on any of the tested cells, we observed that doxycycline induced cell death in selected cancer and primary cell lines. " 02/01/2002 - "These encapsulated cells can be induced to generate sustainable high concentrations NO and reactive nitrogen species at tumor sites after treatment either with ponasterone A or muristerone A or with doxycycline. " 02/01/2008 - "As a first step to defining the potential effects of these inducers, we tested three of them, doxycycline, muristerone A and mifepristone (for tet-, ecdysone- and progesterone antagonist-inducible systems respectively), for toxicity across a panel of normal cells and cancer cell lines. "
3.	Dehydration (Water Stress) 01/01/2002 - "Three ecdysteroid 7,9(11)-dien-7-ones (dacryhainansterone, 25-hydroxydacryhainansterone and kaladasterone) were prepared by dehydration of the corresponding 11a-hydroxy ecdysteroids (ajugasterone C, turkesterone and muristerone A, respectively). "
4.	Common Cold 09/20/2002 - "We have engineered dihydrofolate reductase-deficient (dhfr(-)) Chinese hamster ovary (CHO)-DUKX B11 cells adapted for growth in serum-free suspension cultures for unlinked muristerone-inducible expression of the cyclin-dependent kinase inhibitor p27Kip1 and constitutive expression of the soluble intercellular adhesion molecule-1 (sICAM), a potent common cold therapeutic. "

Related Drugs and Biologics

1.	Doxycycline (Periostat)
2.	Ecdysteroids
3.	Reactive Nitrogen Species
4.	Cyclin-Dependent Kinases (cdk Proteins)
5.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
6.	Mifepristone (RU 486)
7.	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)
8.	Suspensions
9.	Progesterone
10.	Ecdysone

Related Therapies and Procedures

1.	Aftercare (After-Treatment)