deoxyartemisinin

structure given in first source

Also Known As:

artemisinin, deoxy; 10aH-9,10b-Epoxypyrano(4,3,2-jk)(2)benzoxepin-2(3H)-one, octahydro-3,6,9-trimethyl-, (3R-(3alpha,3abeta,6beta,6abeta,9beta,10aalpha,10bbeta))-

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Free Radicals: 15039
  - Reactive Oxygen Species: 39360
    - Artemisinins: 238
      - deoxyartemisinin: 3
Organic Chemicals: 133
- Free Radicals: 15039
  - Reactive Oxygen Species: 39360
    - Artemisinins: 238
      - deoxyartemisinin: 3
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Artemisinins: 238
        deoxyartemisinin: 3

Experts

1.	Efferth, Thomas: 1 article (01/2021)
2.	Fleischer, Edmond: 1 article (01/2021)
3.	Kadioglu, Onat: 1 article (01/2021)
4.	Klauck, Sabine M: 1 article (01/2021)
5.	Shan, Letian: 1 article (01/2021)
6.	Desrosiers, Matthew R: 1 article (01/2020)
7.	Mittelman, Alexis: 1 article (01/2020)
8.	Weathers, Pamela J: 1 article (01/2020)
9.	Li, Xinxiu: 1 article (02/2015)
10.	Xing, Jie: 1 article (02/2015)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2020 - "For tissue distribution studies, artemisinin or DLA was orally delivered to rats, tissues harvested at 1 h, and blood, urine and feces over 8 h; all were analyzed for artemisinin and deoxyartemisinin by GC-MS. For inflammation, rats received an intraperitoneal injection of water or lipopolysaccharide (LPS) and 70 mg/kg oral artemisinin as pure drug or DLA. "
2.	Cardiotoxicity 01/01/2021 - "Using a chemical library of 374 artemisinin derivatives as a case study, 7 compounds (deoxydihydro-artemisinin, 3-hydroxy-deoxy-dihydroartemisinin, 3-desoxy-dihydroartemisinin, dihydroartemisinin-furano acetate-d3, deoxyartemisinin, artemisinin G, artemisinin B) passed the toxicity filtering process for hepatotoxicity, mutagenicity, tumorigenicity, and reproductive toxicity in addition to cardiotoxicity. "
3.	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 02/01/2015 - "Healthy Chinese subjects (six in each group with the genotypes of CAR 540C/C, 540C/T and 540T/T; all carrying the CYP2B611 genotype) received a recommended two-day oral doses of QHS-piperaquine (PQ) to assess the pharmacokinetics of QHS and its metabolite deoxyartemisinin (DQHS). "

Related Drugs and Biologics

1.	artemisinin (artemisinine)
2.	Lipopolysaccharides
3.	Cytochrome P-450 CYP2B6 (CYP2B6)
4.	Acetates (Acetic Acid Esters)
5.	artemisinin G
6.	artemisinin B
7.	artenimol (dihydroartemisinin)
8.	piperaquine

Related Therapies and Procedures

1.	Intraperitoneal Injections