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1-hydroxypentane-1,1-bisphosphonate

Also Known As:

HPeBP

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphonates: 424
    - Diphosphonates: 11565
      - 1-hydroxypentane-1,1-bisphosphonate: 1

Related Diseases

1.

Bone Resorption

03/01/1988 - "In intact rats, HPeBP given at 0.1 mg P/kg body wt sc for 10 days strongly inhibited bone resorption without affecting bone formation. "
03/01/1988 - "In TPTX rats, HPeBP given at same dose also inhibited bone resorption and enhanced plasma 1,25(OH)2D, intestinal Ca absorption and Ca balance. "
03/01/1988 - "In summary, this study shows that bisphosphonates such as HPeBP with prevailing inhibitory activity on bone resorption induce a marked stimulation of both 1,25(OH)2D production and intestinal Ca absorption. "

Related Drugs and Biologics

1.	Diphosphonates (Bisphosphonates)
2.	hydroxide ion