|1.||Tsokos, George C: 10 articles (11/2005 - 01/2002)|
|2.||Nambiar, Madhusoodana P: 10 articles (05/2005 - 01/2002)|
|3.||Warke, Vishal G: 7 articles (05/2005 - 01/2002)|
|4.||Fisher, Carolyn U: 6 articles (05/2005 - 01/2002)|
|5.||Krishnan, Sandeep: 5 articles (05/2005 - 01/2002)|
|6.||Juang, Yuang-Taung: 4 articles (11/2005 - 11/2002)|
|7.||Tsuzaka, Kensei: 4 articles (08/2005 - 09/2003)|
|8.||Takeuchi, Tsutomu: 4 articles (08/2005 - 09/2003)|
|9.||Tsokos, G C: 4 articles (01/2003 - 03/2001)|
|10.||Yoshimoto, Keiko: 3 articles (08/2005 - 09/2003)|
|1.||Melanoma (Melanoma, Malignant)
11/01/1995 - "The overall survival of melanoma patients with low TCR-zeta chain expression was significantly shorter than that of patients with normal TCR-zeta chain expression (P = 0.0013). "
11/01/1995 - "T cells from patients with diminished TCR-zeta chain expression also showed statistically significant differences in cytokine production pattern, with lower interleukin 2 and IFN-zeta production compared with normal subjects and melanoma patients with normal TCR-zeta chain status. "
11/01/1995 - "The present work investigates changes in T-cell signal transduction proteins including the T-cell receptor-zeta (TCR-zeta) chain and receptor-associated tyrosine kinases in patients with metastatic malignant melanoma. "
|3.||Systemic Lupus Erythematosus (Libman-Sacks Disease)
11/01/2005 - "Finally, we established an enhanced binding of CREM to the TCR zeta-chain promoter in systemic lupus erythematosus cells compared with control T cells. "
05/01/2004 - "Dissecting the molecular mechanisms of TCR zeta chain downregulation and T cell signaling abnormalities in human systemic lupus erythematosus."
01/01/2004 - "TCR zeta-chain abnormalities in human systemic lupus erythematosus."
09/01/2003 - "The reduction or absence of TCR zeta-chain (zeta) expression in systemic lupus erythematosus (SLE) patients is thought to be related to the pathogenesis of SLE. "
04/01/2003 - "[Reduced expression of TCR zeta chain in T cells of patients with systemic lupus erythematosus]."
04/01/2009 - "In peripheral blood, the decrease in TCR zeta chain showed an inverse correlation with the tumor stage as demonstrated by western blotting, confocal microscopy and flow cytometry. "
02/01/2008 - "Increasing involvement of tumor in the lymph node was associated with decreasing TCR zeta chain expression (TI 56%, MI 76%, and NI- 89%). "
01/01/2004 - "Additionally TCR zeta chain expression and spontaneous apoptosis considered as a potential markers of immunosupressive effect exert by tumor were determined. "
10/01/2002 - "Both the FcR gamma-chain and the TCR zeta-chain have been used to construct such cTCR, and both have shown specific cytolytic functions against tumor cells. "
01/01/2001 - "Frequently observed decreased expression of TCR zeta chain and high level of apoptosis among T cells present in tumor microenvironment seems to depend on direct interactions with molecules expressed by tumor. "
|5.||Malignant Pleural Effusion
01/01/2004 - "The role of monocytes/macrophages in TCR-zeta chain downregulation and apoptosis of T lymphocytes in malignant pleural effusions."
01/01/2002 - "Expression of TCR-zeta chain and apoptosis in subpopulations of tumor-associated lymphocytes (TALs) from malignant pleural effusions."
01/01/2001 - "Expression of TCR zeta chain of tumor associated lymphocytes from malignant pleural effusions."
|2.||NF-kappa B (NF-kB)
|3.||Proteins (Proteins, Gene)
|4.||Lymphocyte Specific Protein Tyrosine Kinase p56(lck) (p56 lck)
|5.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|6.||T-Cell Antigen Receptors (T-Cell Receptor)
|7.||Antigen Receptors (Antigen Receptor)
|8.||Messenger RNA (mRNA)
|10.||Transcription Factors (Transcription Factor)