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Ro 11-2933

analog of tiapamil

Also Known As:

3,4-DMDP; N-(3,4-dimethyloxyphenethyl)-N-methyl-2-(2-naphthyl)-1,3-dithiane-2-propylamine; Ro-11-2933

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Propylamines: 1
    - Ro 11-2933: 2

Related Diseases

1.	Neoplasms (Cancer) 02/28/1990 - "The ability of RO 11-2933 to restore cellular sensitivity to doxorubicin (DX) was investigated in cultured human cancer cells with two different levels of treatment-induced resistance to DX. " 01/01/1990 - "A reversal of both Doxorubicin or Cisplatin resistance has been observed when P388/Dx or L1210/CP tumor bearing mice received multiple treatments of the antitumor agent plus 30 mg/Kg of RO 11-2933. "
2.	Ovarian Neoplasms (Ovarian Cancer) 02/28/1990 - "In vitro reversal of doxorubicin resistance by the tiapamil analog RO 11-2933 in human ovarian cancer cells."
3.	Leukemia 01/01/1990 - "The ability of RO 11-2933 to modulate in vivo Doxorubicin and Cisplatin antitumor activity has been evaluated in sensitive and resistant P388 and L1210 murine leukemias. " 01/01/1990 - "Reversal of doxorubicin and cisplatin resistance in vivo in murine leukemias by the calcium antagonist RO 11-2933."

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Tiapamil Hydrochloride
3.	Cisplatin (Platino)
4.	Calcium
5.	Antineoplastic Agents (Antineoplastics)