structure given in first source
Also Known As:
Networked: 17 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Safe, Stephen: 4 articles (01/2012 - 04/2004)
2. Zhang, Shu: 2 articles (01/2012 - 09/2009)
3. Liu, Xinyi: 2 articles (01/2012 - 09/2009)
4. Yeguvapalli, Suneetha: 1 article (01/2014)
5. Berke, Adrienne: 1 article (01/2014)
6. Chang, Mary Wu: 1 article (01/2014)
7. McCusker, Meagen: 1 article (01/2014)
8. Finch, Justin: 1 article (01/2014)
9. Chitrala, Kumaraswamy Naidu: 1 article (01/2014)
10. Amendt, Brad: 1 article (01/2012)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Benign Fibrous Histiocytoma (Dermatofibroma)
4. Neoplasm Metastasis (Metastasis)
5. Hepatocellular Carcinoma (Hepatoma)
05/01/1989 - "MCDF did not significantly decrease levels of occupied nuclear Ah receptor complexes in the rat or rat hepatoma cells. "
05/01/1989 - "The effects of MCDF on the uptake and persistence of nuclear [3H]TCDD-Ah receptor complex levels were also determined in rat liver and rat hepatoma H-4-II E cells in culture. "
02/01/1988 - "However, in contrast to TCDD, MCDF was only a weak inducer of AHH and EROD activity in rat hepatoma H-4-II cells in culture. "
05/01/1989 - "In contrast, treatment of rat hepatoma H-4-II E cells with TCDD (10(-8) M) resulted in the rapid (within 1 hr) depletion of cytosolic Ah receptor, which remained undetectable for up to 36 hr; cotreatment of the cells with MCDF (10(-7) M) and TCDD (10(-8) M) resulted in cytosolic Ah receptor levels that were similar to those observed after treatment with TCDD alone. "
05/01/1989 - "Cotreatment of male Long Evans rats with MCDF (50 mumol/kg) and a dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) that causes a near-maximal induction of hepatic microsomal aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase activities resulted in a significant inhibition of these activities for up to 96 hr. Comparable results were obtained with MCDF (10(-7) M) and TCDD (10(-8) M) in rat hepatoma H-4-II E cells in culture over 36 hr. TCDD treatment of rats resulted in an initial decrease of hepatic cytosolic Ah receptor within 6 hr and this was followed by a subsequent 138% increase in cytosolic receptor levels 72 hr after treatment. "

Related Drugs and Biologics

1. 6-methyl-1,3,8-trichlorodibenzofuran
2. Tetrachlorodibenzodioxin (TCDD)
3. Hormones
4. dibenzofuran
5. Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
6. Cytochrome P-450 CYP1A1 (CYP1A1)
7. Proteins (Proteins, Gene)
8. Estrogens (Estrogen)
9. Estradiol (Estrace)
10. Estrogen Receptor Modulators (Antiestrogen)

Related Therapies and Procedures

1. Aftercare (After-Treatment)