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Sch 24937
Also Known As:
6-bromo-5-chloro-2-((methylsulfinyl)acetyl)-3-(2-pyridyl)indole; Sch-24937; Ethanone, 1-(6-bromo5-chloro-3-(2-pyridinyl)-1H-indol-2-yl)-2-(methylsulfonyl)-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Sch 24937: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
Sch 24937: 2
Related Diseases
1.
Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/01/1987 - "
The activity of Sch 24937 in rat models of adjuvant arthritis and experimental allergic encephalomyelitis is also described.
"
2.
Experimental Arthritis
01/01/1987 - "
The activity of Sch 24937 in rat models of adjuvant arthritis and experimental allergic encephalomyelitis is also described.
"
3.
Arthritis (Polyarthritis)
01/01/1990 - "
While the exact mechanism of the immunosuppressive activity of Sch 24937 remains to be elucidated, its mode of action in suppressing arthritis differs at least to some extent from that of a steroid.
"
01/01/1990 - "
Sch 24937 reduced the incidence and severity of arthritis in collagen sensitized mice which appeared to be directly related to the immunosuppressive properties of the drug.
"
01/01/1990 - "
Inhibition of collagen II-induced arthritis in mice--a comparison of the effects of Sch 24937, immunosuppressants and nonsteroidal antiinflammatory drugs on the clinical expression of disease.
"
01/01/1990 - "
These findings prompted an evaluation of the effects of Sch 24937 in type II collagen-induced arthritis in mice where disease manifestations include the development of a strong humoral response to the collagen antigen.
"
Related Drugs and Biologics
1.
Collagen Type II (Type II Collagen)
2.
Steroids
3.
Immunosuppressive Agents (Immunosuppressants)
4.
Collagen
5.
Antigens