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N-dansyl-(1,4-guanidino)phenylalanine piperdide

Also Known As:

I 2581; I-2581

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Phenylalanine: 4090
      - N-dansyl-(1,4-guanidino)phenylalanine piperdide: 2
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Phenylalanine: 4090
        N-dansyl-(1,4-guanidino)phenylalanine piperdide: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - N-dansyl-(1,4-guanidino)phenylalanine piperdide: 2

Related Diseases

1.	Bone Resorption 02/17/1988 - "The effect of two synthetic serine esterase inhibitors, N-alpha-dansyl(p-guanidino)phenylalaninepiperidine hydrochloride (I 2581) and D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (D-Phe-Pro-Arg-CH2Cl), on bone resorption in organ cultured mouse calvaria from neonatal mice has been examined. "
2.	Body Weight (Weight, Body) 08/15/1990 - "Similarly, the inhibitory activity on acetylthrombin was dependent on the molecular weights of the inhibitors, Thromstop, I-2581, hirudin, and antithrombin-III. When acetylthrombin (5000 units/kg body weight) was infused into rabbits, the activated partial thromboplastin time was prolonged to the same extent as that following infusion of thrombin (125 units/kg), but the fibrinogen level was not decreased in contrast to the large decrease following infusion of thrombin. "

Related Drugs and Biologics

1.	Thrombin
2.	Ketones
3.	Hirudins
4.	Fibrinogen (Factor I)
5.	Arginine (L-Arginine)
6.	Antithrombin III
7.	1- myristoyl- 2- (12- ((5- dimethylamino- 1- naphthalenesulfonyl)amino)dodecanoyl)- sn- glycero- 3- phosphocholine
8.	N(alpha)- (2- naphthylsulfonylglycyl)- 4- amidinophenylalanine piperidide (NAPAP)
9.	serine esterase