enisoprost

Also Known As:

11,16-dihydroxy-16-methyl-9-oxoprost-4,13-dien-1-oic acid

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Alprostadil: 3107
        enisoprost: 7
    - Monounsaturated Fatty Acids: 676
      - Alprostadil: 3107
        enisoprost: 7
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Alprostadil: 3107
        enisoprost: 7

Related Diseases

1.	Burns 05/01/1995 - "Additional animals were treated with enisoprost (prostaglandin E1 (PGE1) analog) 200 micrograms/kg/day orally for 3 days before burn. " 08/01/1993 - "Balb/c mice were treated with misoprostol (n = 36) or enisoprost (n = 36) for 3 days with different doses (20 or 200 micrograms/kg/day) prior to receiving a 20% full-thickness burn and simultaneous gavage with 1 x 10(10) 14C-Escherichia coli. " 08/01/1993 - "The aim of this study was to investigate the ability of two prostaglandin E1 (PGE1) analogues, misoprostol and enisoprost, to alter bacterial translocation following burn injury. " 10/01/1992 - "In the next experiment, the prostaglandin E (PGE) analogs misoprostol, enisoprost, or 16,16-dimethyl PGE2 were administered to transfused animals for 3 days before burn. "
2.	Peptic Ulcer (Peptic Ulcers) 08/01/1988 - "The results of this study suggest that enisoprost should be tested by clinical trial for the treatment of peptic ulcer disease."
3.	Inflammation (Inflammations) 12/01/1992 - "When given as enemas 30 min ahead of colitis induction, 15(R)-15-methyl-PGE2 (arbaprostil) and 15(S)-15-methyl-PGE1 were inactive; however, misoprostol, enisoprost, and SC-46275 protected against colonic inflammation with ED50 values of 24, 12 and 1.3 micrograms/kg, respectively, in rats and 11, 5, and 1 micrograms/kg, respectively, in mice. "
4.	Hyperalgesia 02/01/1995 - "Five synthetic prostaglandin E analogs (11-deoxyPGE1, 17-phenyl-ol-trinor prostaglandin E2, enisoprost, MB28767 and misoprostol) have been evaluated for their ability to produce mechanical hyperalgesia in rats. " 02/01/1995 - "Hyperalgesia produced by 17-phenyl-ol-trinor prostaglandin E2 and MB28767, was inhibited by the prostaglandin E1 antagonist SC19220 (7.5 ng), while the hyperalgesia produced by 11-deoxyprostaglandin E1, enisoprost and misoprostol was not inhibited by this antagonist. "
5.	Diabetes Mellitus 04/01/1992 - "Effect of the prostaglandin E1 analog enisoprost on glucose and lipid metabolism in patients with type II diabetes mellitus."

Related Drugs and Biologics

1.	Misoprostol (Cytotec)
2.	Alprostadil (Muse)
3.	Dinoprostone (PGE2)
4.	Synthetic Prostaglandins (Prostaglandin Analogues)
5.	Acetic Acid (Vinegar)
6.	Prostaglandins E
7.	Prostaglandins
8.	Glucose (Dextrose)
9.	Arbaprostil
10.	SC-46275

Related Therapies and Procedures

1.	Enema (Enemas)