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enisoprost
Also Known As:
11,16-dihydroxy-16-methyl-9-oxoprost-4,13-dien-1-oic acid
Networked:
7
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Alprostadil: 3107
enisoprost: 7
Monounsaturated Fatty Acids: 676
Alprostadil: 3107
enisoprost: 7
Biological Factors: 2472
Inflammation Mediators: 1113
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Alprostadil: 3107
enisoprost: 7
Related Diseases
1.
Burns
05/01/1995 - "
Additional animals were treated with enisoprost (prostaglandin E1 (PGE1) analog) 200 micrograms/kg/day orally for 3 days before burn.
"
08/01/1993 - "
Balb/c mice were treated with misoprostol (n = 36) or enisoprost (n = 36) for 3 days with different doses (20 or 200 micrograms/kg/day) prior to receiving a 20% full-thickness burn and simultaneous gavage with 1 x 10(10) 14C-Escherichia coli.
"
08/01/1993 - "
The aim of this study was to investigate the ability of two prostaglandin E1 (PGE1) analogues, misoprostol and enisoprost, to alter bacterial translocation following burn injury.
"
10/01/1992 - "
In the next experiment, the prostaglandin E (PGE) analogs misoprostol, enisoprost, or 16,16-dimethyl PGE2 were administered to transfused animals for 3 days before burn.
"
2.
Peptic Ulcer (Peptic Ulcers)
08/01/1988 - "
The results of this study suggest that enisoprost should be tested by clinical trial for the treatment of peptic ulcer disease.
"
3.
Inflammation (Inflammations)
12/01/1992 - "
When given as enemas 30 min ahead of colitis induction, 15(R)-15-methyl-PGE2 (arbaprostil) and 15(S)-15-methyl-PGE1 were inactive; however, misoprostol, enisoprost, and SC-46275 protected against colonic inflammation with ED50 values of 24, 12 and 1.3 micrograms/kg, respectively, in rats and 11, 5, and 1 micrograms/kg, respectively, in mice.
"
4.
Hyperalgesia
02/01/1995 - "
Five synthetic prostaglandin E analogs (11-deoxyPGE1, 17-phenyl-ol-trinor prostaglandin E2, enisoprost, MB28767 and misoprostol) have been evaluated for their ability to produce mechanical hyperalgesia in rats.
"
02/01/1995 - "
Hyperalgesia produced by 17-phenyl-ol-trinor prostaglandin E2 and MB28767, was inhibited by the prostaglandin E1 antagonist SC19220 (7.5 ng), while the hyperalgesia produced by 11-deoxyprostaglandin E1, enisoprost and misoprostol was not inhibited by this antagonist.
"
5.
Diabetes Mellitus
04/01/1992 - "
Effect of the prostaglandin E1 analog enisoprost on glucose and lipid metabolism in patients with type II diabetes mellitus.
"
Related Drugs and Biologics
1.
Misoprostol (Cytotec)
2.
Alprostadil (Muse)
3.
Dinoprostone (PGE2)
4.
Synthetic Prostaglandins (Prostaglandin Analogues)
5.
Acetic Acid (Vinegar)
6.
Prostaglandins E
7.
Prostaglandins
8.
Glucose (Dextrose)
9.
Arbaprostil
10.
SC-46275
Related Therapies and Procedures
1.
Enema (Enemas)