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structure given in first source; RN from Toxline
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Bio-Agent Context: Research Results
Heterocyclic Compounds: 60
2-Ring Heterocyclic Compounds
McN 4130: 2
05/01/1988 - "
In anesthetized normal dogs, McN-4130 increased ventricular fibrillation threshold for up to 45 min. This increase in fibrillation threshold was associated with concurrent increases in ventricular conduction time and ventricular effective refractory period.
Cardiac Arrhythmias (Arrythmia)
11/01/1987 - "
McN-4130 has antiarrhythmic efficacy in a number of animal models of ventricular arrhythmia and fibrillation.
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