ZK 91587

Also Known As:

7 alpha-methoxycarbonyl-15 beta,16 beta-methylene-3-oxo-17 alpha-pregn-4-ene-21,17-carbolactone; 3'H-Cyclopropa(15,16)pregna-4,15-diene-7,21-dicarboxylic acid, 15,16-dihydro-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,15alpha,16alpha,17alpha)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Spironolactone: 3235
    - ZK 91587: 1
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Spironolactone: 3235
        ZK 91587: 1

Experts

1.	Agarwal, M K: 1 article (04/2000)
2.	Golestaneh, N: 1 article (04/2000)
3.	Mirshahi, M: 1 article (04/2000)
4.	Valamanesh, F: 1 article (04/2000)

Related Diseases

1.	Leukemia 04/21/2000 - "Paradoxically, the MCR-specific antagonist ZK 91587 actually stimulated the multiplication of human erythroblastic leukemia cells, contrary to the inhibitory effect of the antagonist RU 26752 on the multiplication of corneal fibroblasts; both effects were opposed by aldosterone. "

Related Drugs and Biologics

1.	Aldosterone
2.	7-propyl spirolactone