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manumycin

an NSAID; RN given for (1S-(1alpha,3(2E,4E,6S*),5alpha,5(1E,3E,5E),6alpha))-isomer; a farnesyl protein transferase inhibitor; from Streptomyces parvulus; MF C31-H38-N2-O7; structure given in first source
Also Known As:
UCFI-C; manumycin A; 2,4-Decadienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-2,4,6-trimethyl-
Networked: 61 relevant articles (2 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yeung, Sai-Ching Jim: 6 articles (10/2008 - 03/2002)
2. Sun, Lily: 4 articles (10/2008 - 02/2003)
3. Sen, Ellora: 3 articles (01/2015 - 08/2009)
4. Pan, Jingxuan: 3 articles (10/2008 - 06/2005)
5. Liu, Zong-Chao: 3 articles (08/2005 - 06/2003)
6. Pan, Qi-Chao: 3 articles (08/2005 - 06/2003)
7. Zhou, Jun-Min: 3 articles (08/2005 - 06/2003)
8. Zhu, Xiao-Feng: 3 articles (08/2005 - 06/2003)
9. Pan, J: 3 articles (10/2001 - 02/2000)
10. Xu, G: 3 articles (10/2001 - 02/2000)

Related Diseases

1. Prostatic Neoplasms (Prostate Cancer)
2. Carcinogenesis
3. Colorectal Neoplasms (Colorectal Cancer)
4. Anaplastic Thyroid Carcinoma
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Farnesyltranstransferase (Farnesyltransferase)
2. Paclitaxel (Taxol)
3. manumycin
4. hypericin
5. Transferases
6. Proteins (Proteins, Gene)
7. Reactive Oxygen Species (Oxygen Radicals)
8. Antineoplastic Agents (Antineoplastics)
9. Cytochromes c (Cytochrome c)
10. Mitogen-Activated Protein Kinases

Related Therapies and Procedures

1. Chemoprevention
2. Aftercare (After-Treatment)
3. Intraperitoneal Injections
4. Castration