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curcuphenol

from marine sponge Epipolasis sp.; inhibts H,K-ATPase; structure given in first source; RN given refers to (R)-isomer

Also Known As:

curcuphenol, (S)-isomer

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - curcuphenol: 3

Experts

1.	Gul, Waseem: 1 article (11/2007)
2.	Hamann, Mark T: 1 article (11/2007)
3.	Hammond, Nicholas L: 1 article (11/2007)
4.	Holley, Andy: 1 article (11/2007)
5.	Peng, Jiangnan: 1 article (11/2007)
6.	Yousaf, Muhammad: 1 article (11/2007)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2023 - "Curcuphenol, a common component of the culinary spices, naturally found in marine invertebrates and plants, has been identified as a novel candidate for reversing immune escape by restoring expression of the antigen presentation machinery (APM) in invasive cancers, thereby resurrecting the immune recognition of metastatic tumours. " 01/01/2023 - "Turmeric and curcumins that contain curcuphenol have long been utilized not only as a spice in the preparation of food, but also in traditional medicines for treating cancers. "
2.	Carcinoma (Carcinomatosis) 01/01/2023 - "Two synthetic curcuphenol analogues, were prepared by informed design that demonstrated consistent induction of APM expression in metastatic prostate and lung carcinoma cells. " 01/01/2023 - "We demonstrate that curcuphenol induces the expression of the APM components, TAP-1 and MHC-I molecules, in cell lines derived from both metastatic prostate and lung carcinomas. "
3.	Communicable Diseases (Infectious Diseases) 11/01/2007 - "In order to optimize the activity and better understand the SAR of (S)-(+)-curcuphenol, nineteen semisynthetic analogs were prepared and evaluated for activity against infectious diseases. "

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