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apolipoprotein C-II (St Michael)

a nonfunctional variant of apo C-II, identified at the St. Michaels Hospital, Toronto; substitution at residue 70, glutamine (Q) replaced by proline (P), consistent with a base insertion in the codon for Asp69 or Gln70 in the APOC2 gene and a subsequent translation reading frame shift; associated with premature ischemic vascular disease
Also Known As:
apo C-II (St Michael); apoCIIs; apolipoprotein C-IIs; apolipoprotein CII St Michael
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