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proinsulin endopeptidase I

involved in proteolytic conversion of proinsulin into insulin; pH optimum 5.5; cleaves exclusively on the C-terminal side of Arg 31.Arg 32 (B-chain/C-peptide junction); not inhibited by inhibitors of aspartic proteinases
Also Known As:
Ca-dependent endopeptidase I; calcium-dependent acidic endopeptidase I
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