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trigramin

MW 9kDA; from Trimeresurus gramineus snake venom; inhibits fibrinogen binding to platelet receptors

Also Known As:

Trigramin

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - trigramin: 5
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - trigramin: 5
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - trigramin: 5

Experts

1.	Chuang, Woei-Jer: 1 article (04/2005)
2.	Fu, Wen-Mei: 1 article (04/2005)
3.	Huang, Tsang-Hai: 1 article (04/2005)
4.	Huang, Tur-Fu: 1 article (04/2005)
5.	Peng, Hui-Chin: 1 article (04/2005)
6.	Tang, Chih-Hsin: 1 article (04/2005)
7.	Yang, Rong-Sen: 1 article (04/2005)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2005 - "In contrast, co-administration of trigramin with cancer cells markedly inhibited tumor growth and bone destruction. "
2.	Melanoma (Melanoma, Malignant) 11/01/1988 - "Trigramin, an RGD-containing peptide from snake venom, inhibits cell-substratum adhesion of human melanoma cells." 11/01/1988 - "Trigramin, a cysteine-rich, RGD-containing peptide isolated from the venom of the Trimeresurus gramineus snake, inhibited the adhesion of human melanoma cells to fibronectin and fibrinogen. "
3.	Colonic Neoplasms (Colon Cancer) 06/01/1994 - "Characterization of platelet aggregation induced by human colon adenocarcinoma cells and its inhibition by snake venom peptides, trigramin and rhodostomin."
4.	Breast Neoplasms (Breast Cancer) 03/01/1995 - "Characterization of platelet aggregation induced by human breast carcinoma and its inhibition by snake venom peptides, trigramin and rhodostomin."
5.	Adenocarcinoma 04/01/1996 - "Characterisation of platelet aggregation induced by PC-3 human prostate adenocarcinoma cells and inhibited by venom peptides, trigramin and rhodostomin."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Snake Venoms (Snake Venom)
3.	rhodostomin
4.	Venoms
5.	Fibronectins (Fibronectin)
6.	Fibrinogen (Factor I)
7.	Cysteine (L-Cysteine)