|1.||Liu, Fei: 7 articles (01/2014 - 10/2011)|
|2.||Cao, Jianguo: 5 articles (01/2014 - 11/2011)|
|3.||Tian, Li: 5 articles (05/2013 - 10/2011)|
|4.||Quan, Meifang: 4 articles (01/2014 - 05/2012)|
|5.||Zhou, Yuan: 3 articles (01/2014 - 01/2013)|
|6.||Bae, Hyunsu: 2 articles (10/2015 - 07/2011)|
|7.||Sheng, Xifeng: 2 articles (05/2012 - 11/2011)|
|8.||Cai, Bing: 2 articles (08/2005 - 01/2005)|
|9.||Choi, Woosung: 1 article (10/2015)|
|10.||Lee, Hyeonhoon: 1 article (10/2015)|
12/02/2014 - "Previous studies found that casticin, isolated from Vitex rotundifolia, could induce apoptosis of tumor cells. "
05/01/2012 - "The purpose of this study was to examine the apoptotic activity of casticin on human cervical cancer cells and its molecular mechanism. "
11/01/2011 - "The purpose of this study was to examine the apoptotic activity and molecular mechanism of casticin action on human cervical cancer cells. "
01/01/2013 - "Recently, casticin has drawn wide attention to its critical role in tumor progression. "
01/01/2013 - "Casticin is one of the main active components obtained from Fructus Viticis and has been reported to exert anti-carcinogenic activity on a variety of cancer cells but the precise mechanism underlying this activity remains unclear. "
12/01/2013 - "In this study, the effects of Vitex and its major component, casticin, on leukemia cell lines, HL-60 and U-937, were investigated by focusing on proliferation, induction of apoptosis and differentiation. "
08/01/2009 - "This study aims to examine the anti-leukemic activity of casticin on leukemia cells and its molecular mechanism. "
12/01/2013 - "Since the HL-60 cell line is more immature than the U-937 cell line, these results suggested that the levels of cytotoxicity of Vitex/casticin were largely attributed to the degree of differentiation of leukemia cells; that is, cell lines with less differentiated phenotype were more susceptible than the differentiated ones. "
12/01/2013 - "Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines."
08/01/2009 - "Taken together, these results demonstrated that casticin induced leukemic cell death via apoptosis and mitotic catastrophe, and could synergize with PI3K/AKT inhibitor, suggesting that casticin could be a promising therapeutic agent against leukemia."
04/01/2012 - "In this study, we investigated whether vitexicarpin (5-100 nM) prevented the TNF-α-induced vascular inflammation process in human umbilical vein endothelial cells (HUVEC). "
12/02/2014 - "RAW264.7 cells were pretreated with various concentrations of casticin (0.3-10μM), and then treated with LPS to induce inflammation. "
04/01/2012 - "In conclusion, vitexicarpin significantly reduced vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells."
09/01/2007 - "Casticin has significant anti-inflammatory effect on acute inflammation, which is probably related to the inhibition of the inflammation factors. "
09/01/2007 - "Observations were made on the anti-inflammatory effect of casticin in the models of acute inflammation in vivo. "
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/2013 - " The objectives of this study were to examine the molecular mechanisms by which casticin induces the growth inhibition and cell cycle arrest in human hepatocellular carcinoma (HCC) cells. "
01/01/2013 - "Casticin induces growth suppression and cell cycle arrest through activation of FOXO3a in hepatocellular carcinoma."
10/14/2011 - "To investigate the apoptotic activities of casticin in hepatocellular carcinoma (HCC) cells and its molecular mechanisms. "
10/14/2011 - "Casticin-induced apoptosis involves death receptor 5 upregulation in hepatocellular carcinoma cells."
10/01/2015 - "The results of this study indicate that casticin has significant effects on the lung inflammation induced by CS in a mouse model. "
10/01/2015 - "The aim of this study was to determine of the effect of casticin, as an anti-inflammatory agent, on an acute lung inflammation in vivo model established through exposure to cigarette smoke (CS). "
|4.||TNF-Related Apoptosis-Inducing Ligand Receptors
|5.||Reactive Oxygen Species (Oxygen Radicals)
|7.||Propidium (Propidium Iodide)
|9.||Caspase 3 (Caspase-3)
|10.||Apoptosis Regulatory Proteins
|1.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|2.||Traditional Medicine (Folk Remedies)