sesamin

10/01/2015 - "Chronic treatment with sesamin could reduce hypertension and improve endothelial dysfunction through enhancement of NO bioactivity in SHR aortas."
10/12/2009 - "All these results suggest that chronic treatment with sesamin reduces hypertension and improves endothelial dysfunction through upregulation of eNOS expression and reduction of NO oxidative inactivation in 2K1C rats on HFS diet."
02/01/2009 - "It has been reported that sesamin suppressed the development of hypertension in rats. "
12/01/2004 - "From the above results, it is suggested that sesamin may improve hypertension by its ability to induce NO and inhibit ET-1 production from endothelial cells. "
09/01/2000 - "Sesamin feeding significantly suppressed the development of this hypertension (167.1+/-8.6 mmHg). "

12/01/2019 - "Protective Effects of Sesamin against UVB-Induced Skin Inflammation and Photodamage In Vitro and In Vivo."
05/31/2017 - "Sesamin enhances CSPGs synthesis, suppresses IL-1β expression and ameliorates IL-1β induced inflammation in human chondrocytes. "
01/01/2016 - "Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα."
07/01/2023 - "In addition, the transcription examination by qRT-PCR of oxidative- and inflammation-related genes showed that sesamin affected the genes in a manner that correlated with results from the efficacy assays. "
03/01/2023 - "Histological examinations showed that sesamin treatment mitigated the progression of hepatic steatosis, and inflammation. "

07/01/2022 - "Sesamin: Insights into its protective effects against lead-induced learning and memory deficits in rats."
11/10/2016 - "This study investigated the effects of (-)-sesamin on memory deficits induced by chronic electric footshock (EF)-induced stress in mice. "
07/01/2022 - "This data suggests that sesamin could improve Pb-induced learning and memory deficits, possibly through amelioration of hippocampal theta and gamma rhythms, modulation of inflammatory status, restoration of the blood δ-ALA-D activity, reduction of Pb accumulation in the blood and the brain tissues, and prevention of neuronal loss."
11/10/2016 - "Effects of (-)-sesamin on chronic stress-induced memory deficits in mice."
01/01/2019 - "These results illustrated that sesamin markedly improved CUMS-induced depression and memory loss via inhibiting neuroinflammation, which indicate that as food component, sesamin might be also a novel potential therapeutic for depression."

06/29/2022 - "What is more, by the high-fat diet induced obese model, we further showed that sesamin improved the high-fat diet induced decrease in irisin production and secretion, which results in an improvement of body weight gain and skeletal muscle dysfunction. "
03/15/2014 - "This is consistent with lower body weights found in fish fed high sesamin content."
05/01/1998 - "The left ventricle plus septum weight-to-body weight ratio was slightly but significantly lowered by sesamin feeding. "
03/01/2023 - "The results suggested that sesamin-treated mice lost body weight and fat tissue weight, had lower levels of serum metabolic parameters, and insulin resistance was mitigated. "
02/01/2023 - "The protective effects of sesamin on ALI were investigated using the survival rate, lung/body weight ratio, histological analysis of lung with HE staining, and mRNA levels of inflammatory factors. "

01/01/2019 - "Moreover, sesamin treatment significantly prevented CUMS-induced neuroinflammation by inhibiting over-activation of microglia and expressions of inflammatory mediators including iNOS, COX-2, TNF-α and IL-1β in stressed mice hippocampus and cortex. "
01/01/2019 - "These results illustrated that sesamin markedly improved CUMS-induced depression and memory loss via inhibiting neuroinflammation, which indicate that as food component, sesamin might be also a novel potential therapeutic for depression."
01/01/2014 - "Several studies have reported that sesamin is effective in preventing hypertension, thrombotic tendency, and neuroinflammation. "
01/01/2019 - "(+)-Sesamin attenuates chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits via suppression of neuroinflammation."
01/01/2012 - "Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system."