|1.||Kiso, Yoshinobu: 9 articles (03/2011 - 09/2002)|
|2.||Ono, Yoshiko: 6 articles (11/2015 - 04/2008)|
|3.||Kong, Xiang: 6 articles (10/2015 - 10/2009)|
|4.||Yang, Jie-Ren: 4 articles (10/2015 - 10/2009)|
|5.||Shibata, Hiroshi: 3 articles (11/2015 - 02/2011)|
|6.||Hou, Chien-Wei: 3 articles (04/2015 - 01/2011)|
|7.||Jeng, Kee-Ching: 3 articles (04/2015 - 01/2011)|
|8.||Yang, Jie-ren: 3 articles (04/2015 - 02/2013)|
|9.||Tomimori, Namino: 3 articles (01/2015 - 07/2009)|
|10.||Lin, Ching-Huei: 3 articles (09/2014 - 01/2011)|
|1.||Hypertension (High Blood Pressure)
01/01/2014 - "Several studies have reported that sesamin is effective in preventing hypertension, thrombotic tendency, and neuroinflammation. "
10/01/2015 - "Chronic treatment with sesamin could reduce hypertension and improve endothelial dysfunction through enhancement of NO bioactivity in SHR aortas."
10/12/2009 - "All these results suggest that chronic treatment with sesamin reduces hypertension and improves endothelial dysfunction through upregulation of eNOS expression and reduction of NO oxidative inactivation in 2K1C rats on HFS diet."
02/01/2009 - "It has been reported that sesamin suppressed the development of hypertension in rats. "
03/01/2008 - "1. Dietary sesamin, a sesame lignan, is known to suppress the development of experimental hypertension in rats partly through its inhibitory effect on vascular O(2)(-) production. "
12/01/2014 - "The present study was designed to evaluate molecular mechanism by which sesamin (SES) induces neuroprotection in mouse model of ischemic stroke. "
12/01/2014 - "Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke."
01/05/2010 - "Thus, sesamin may be a potential compound in stroke therapy."
05/01/1998 - "The antihypertensive effect of sesamin, a lignan from sesame oil, was examined using salt-loaded and unloaded stroke-prone spontaneously hypertensive rats (SHRSP). "
03/15/1993 - "Effects of sesamin on serum lipoprotein metabolism in normocholesterolemic and hypercholesterolemic stroke-prone SHR."
01/01/2015 - "Sesamin is one of the major components in sesame seeds and has been widely studied and proven to have anti-proliferation and anti-angiogenic effects on cancer cells. "
04/15/2014 - "The microarray expression profile, which predicted sensitivity or resistance of tumor cells to (-)-sesamin consisted of genes, which do not belong to the classical resistance mechanisms to established anticancer drugs. "
04/15/2014 - "In conclusion, (-)-sesamin is not involved in MDR mediated by ABCB1 or ABCB5 and may be valuable to bypass chemoresistance of refractory tumors. "
04/15/2014 - "The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance."
01/01/2014 - "Food-derived sesamin directs the epithelial differentiation of cancer stem-like SP cells from GBC, which is associated with attenuation of NF-κB-IL-6-Stat3-Twist signal pathway."
01/01/2015 - "This study investigated the effect of sesamin on myocardial fibrosis in spontaneously hypertensive rats (SHRs) and the possible mechanisms involved. "
01/01/2015 - "These data suggest that sesamin is capable of attenuating hypertensive myocardial fibrosis through, at least partly, suppression of TGF-β1/Smad signaling pathway. "
01/01/2015 - "Suppression of TGF-β1/Smad signaling pathway by sesamin contributes to the attenuation of myocardial fibrosis in spontaneously hypertensive rats."
09/01/2014 - "The effect of sesamin on airway fibrosis in vitro and in vivo."
09/01/2014 - "Histological studies revealed that sesamin protected against subepithelial fibrosis by reducing myofibroblast activation and collagen accumulation in the ECM. "
|5.||Parkinson Disease (Parkinson's Disease)
04/01/2015 - "Effects of (-)-sesamin on 6-hydroxydopamine-induced neurotoxicity in PC12 cells and dopaminergic neuronal cells of Parkinson's disease rat models."
01/01/2005 - "The aim of this study was to determine whether sesamin, a component from Acanthopanax senticosus HARMS (ASH) pharmacologically offers protection against Parkinson's disease (PD) and its related depressive behavior in rats administered rotenone. "
04/01/2015 - "The present study investigated the effects of (-)-sesamin on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity using PC12 cells and dopaminergic neuronal cells of 6-OHDA-lesioned rat model of Parkinson's disease (PD). "
|5.||Sesame Oil (Oil, Sesame)
|7.||NF-kappa B (NF-kB)
|8.||Toll-Like Receptor 4
|9.||Collagen Type I (Type I Collagen)
|10.||Kainic Acid (Kainate)
|1.||Surgical Instruments (Clip)
|2.||Drug Therapy (Chemotherapy)