1- methyl- 4- cyclohexyl- 1,2,3,6- tetrahydropyridine

Subscribe to Selected New Research on 1-methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine

46 relevant articles (0 outcomes, 4 trials/studies) found for this Bio-Agent

Also Known As:

MCTP

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Pyridines: 26

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: 1753

1-methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine: 46

Related Diseases

1.	Pulmonary Hypertension (Ayerza Syndrome) 07/01/1993 - "In summary, MCTP treatment of rats decreases the fibrinolytic activity of lung tissue relatively early after exposure to the toxicant and before the onset of pulmonary hypertension" 01/01/1991 - "These results indicate that MCTP causes a direct, dose-dependent injury to pulmonary vascular endothelium in culture that is delayed and progressive and suggest a mechanism by which MCT may act in vivo to cause lung injury and pulmonary hypertension." 01/01/1991 - "A single, iv injection of chemically synthesized MCTP into rats causes delayed and progressive lung vascular injury and pulmonary hypertension similar to that caused by MCT itself" 06/15/1989 - "These results support the hypothesis that the development of MCTP-induced pulmonary hypertension is mediated in part by platelets." 11/01/1988 - "These data indicate that moderate reduction of the number of circulating platelets prevents MCTP-induced pulmonary hypertension but not MCTP-induced lung injury, suggesting that the platelet is involved in the pulmonary hypertensive response to MCTP-induced lung injury by unknown mechanisms." Get all the results and reference details, order at left...
2.	Hypertrophy 04/28/1998 - "CONCLUSIONS: In the setting of MCTP-induced CPH, significant worsening of RV diastolic function was observed in association with significant increases in the ratio of RV dry weight to LV+septal dry weight, suggesting that these changes are partially due to RV hypertrophy" 06/01/1994 - "At Day 14 only, the hearts of MCTP-treated rats appeared enlarged and there was right cardioventricular hypertrophy" 07/01/1991 - "Right cardioventricular hypertrophy was first detected at 8 days in MCTP-treated rats and became more pronounced with time" 03/01/1991 - "Progressive and marked endothelial cell hypertrophy occurred after exposure to a nominal concentration of 5 or 50 micrograms/ml of MCTP but not after 0.5 micrograms/ml. Morphologic changes in monolayers of BSMCs were minimal, even up to 2 weeks after exposure" 07/01/1997 - "These results demonstrate that MCTP causes thickening of the media of pulmonary vessels through VSMC hypertrophy and that the prolonged DNA synthesis that accompanies VSMC hypertrophy is not followed by proliferation." Get all the results and reference details, order at left...
3.	Vascular Diseases (Vascular Disease) 01/26/1996 - "The monocrotaline pyrrole (MCTP)-treated rat is a useful model for the study of certain chronic pulmonary vascular diseases" Get all the results and reference details, order at left...
4.	Bronchopulmonary Sequestration (Pulmonary Sequestration) 06/15/1989 - "To study the role of platelets in monocrotaline pyrrole (MCTP)-induced pulmonary hypertension, pulmonary sequestration of 111In-labeled platelets in rats treated with MCTP and anti-rat platelet serum (PAS) was examined" Get all the results and reference details, order at left...
5.	Right Ventricular Hypertrophy 01/26/1996 - "A single, i.v. administration of a low dose of MCTP causes pneumotoxicity, pulmonary vascular remodeling, sustained increases in pulmonary arterial pressure, and right ventricular hypertrophy in rats" 12/01/1988 - "In addition, right ventricular hypertrophy was manifested by 14 days after MCTP administration" 04/01/1986 - "Moreover, MCTP-induced right ventricular hypertrophy was not attenuated by KET" 06/01/1984 - "Fourteen days after MCTP, right ventricular hypertrophy and several indexes of lung injury were measured" 01/26/1996 - "We conclude that an increase in plasma cFn concentration occurs prior to the onset of right ventricular hypertrophy and that this change is consistent with a role for cFn in the genesis of vascular remodeling and pulmonary hypertension in the MCTP-treated rat" Get all the results and reference details, order at left...
18 Diseases and 46 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	monocrotaline pyrrole
2.	p-Aminosalicylic Acid (PAS)
3.	Milrinone (Primacor)
4.	Monocrotaline
5.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)
6.	Proteins (Proteins, Gene)
7.	N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)
8.	SNARE Proteins (SNAREs)
9.	Serotonin (5 Hydroxytryptamine)
10.	Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
34 Drugs and Important Bio-Agents and 39 more articles analyzed in the Research Interface, order at left...

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