|1.||Berry, Gerald J: 1 article (02/2014)|
|2.||Nishimura, Toshihiko: 1 article (02/2014)|
|3.||Trudell, James R: 1 article (02/2014)|
|4.||Qiao, Lina: 1 article (02/2014)|
|5.||Pearl, Ronald G: 1 article (02/2014)|
|6.||Kao, Peter N: 1 article (02/2014)|
|7.||Thrasher, Ama: 1 article (02/2014)|
|8.||Shi, Lingfang: 1 article (02/2014)|
|9.||Sessions, Dane: 1 article (02/2014)|
|10.||Costea, I: 1 article (04/2008)|
|1.||Pulmonary Hypertension (Ayerza Syndrome)
07/01/1993 - "In summary, MCTP treatment of rats decreases the fibrinolytic activity of lung tissue relatively early after exposure to the toxicant and before the onset of pulmonary hypertension. "
06/15/1989 - "These results support the hypothesis that the development of MCTP-induced pulmonary hypertension is mediated in part by platelets."
01/01/1988 - "Although the mechanism by which MCTP causes pulmonary hypertension is unknown, vasoconstriction may play a role. "
04/01/1987 - "Fourteen days following treatment with MCTP when pulmonary hypertension is well-established and RVE is present, the concentration of 5HT in washed platelets or in platelet-poor plasma was not different in treated and control rats. "
01/01/1987 - "These data indicate that MCTP treatment increases the release of TxB2 from isolated lungs at a time when pulmonary hypertension is well-established, but not during early development of pulmonary hypertension."
12/01/1988 - "Data from this study support the hypothesis that platelets are involved in the development of the pulmonary hypertensive response following MCTP-induced lung injury."
07/01/1993 - "Lung injury was evident 3 days after administration of MCTP and became more pronounced with time. "
06/01/1993 - "It has been suggested that the lung injury caused by this compound may be initiated by an interaction between MCTP and cells of the pulmonary vasculature. "
06/01/1991 - "Mature neutrophils had degenerate cytomorphologic characteristics at both 4 and 120 hr. These results confirm that pronounced lung injury is delayed for several days after a single, intravenous administration of MCTP, but they also indicate that subtle lung injury can be detected using quantitative markers quite early after MCTP administration."
06/15/1989 - "When rats were treated similarly with MCTP and PAS and were killed at 18 days, the attenuation of the pulmonary hypertensive response previously described was not observed, and lung injury was more extensive than when CS was given. "
04/28/1998 - "In the setting of MCTP-induced CPH, significant worsening of RV diastolic function was observed in association with significant increases in the ratio of RV dry weight to LV+septal dry weight, suggesting that these changes are partially due to RV hypertrophy. "
06/01/1994 - "At Day 14 only, the hearts of MCTP-treated rats appeared enlarged and there was right cardioventricular hypertrophy. "
07/01/1991 - "Right cardioventricular hypertrophy was first detected at 8 days in MCTP-treated rats and became more pronounced with time. "
03/01/1991 - "Progressive and marked endothelial cell hypertrophy occurred after exposure to a nominal concentration of 5 or 50 micrograms/ml of MCTP but not after 0.5 micrograms/ml. Morphologic changes in monolayers of BSMCs were minimal, even up to 2 weeks after exposure. "
07/01/1997 - "These results demonstrate that MCTP causes thickening of the media of pulmonary vessels through VSMC hypertrophy and that the prolonged DNA synthesis that accompanies VSMC hypertrophy is not followed by proliferation."
|4.||Bronchopulmonary Sequestration (Pulmonary Sequestration)
|5.||Right Ventricular Hypertrophy
02/11/2014 - "Compared with the group vehicle, by day 35, group P/MCTP developed higher right ventricular systolic pressure (54±5 versus 25±2 mm Hg; P<0.01) and right ventricular hypertrophy (0.58±0.16 versus 0.26±0.05; P<0.01). "
12/01/1988 - "In addition, right ventricular hypertrophy was manifested by 14 days after MCTP administration. "
04/01/1986 - "Moreover, MCTP-induced right ventricular hypertrophy was not attenuated by KET. "
06/01/1984 - "When PAS was given 12 h before MCTP, it did not affect right ventricular hypertrophy, but when PAS treatment was begun 3 or 6 days after MCTP, right ventricular hypertrophy was decreased by 19 or 41%, respectively. "
01/01/1987 - "MCTP given intravenously to rats causes pulmonary hypertension and right ventricular hypertrophy. "
|4.||L-Lactate Dehydrogenase (Lactate Dehydrogenase)
|5.||Serotonin (5 Hydroxytryptamine)
|6.||Bovine Serum Albumin
|7.||N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)
|8.||SNARE Proteins (SNAREs)
|9.||6-Ketoprostaglandin F1 alpha (6 Ketoprostaglandin F1 alpha)
|5.||Pneumonectomy (Lung Volume Reduction)