mesenchyme-derived growth factor

05/01/1988 - "The finding that endometriosis is associated with in vivo primed peritoneal macrophages that produce MDGF in vitro may help to explain the proliferation or maintenance of endometrial tissue in the peritoneal cavity."
11/01/2020 - "Although MDGF expression showed an increase in the endometriosis group compared with non-endometriotic controls, no significant difference was found. "
05/01/1988 - "In contrast, macrophages from 13 of 19 (68%) women with endometriosis, a significantly higher proportion (P less than 0.02), released MDGF. "
11/01/2020 - "Vitamin D3 significantly decreased EGF expression at 6, 24 and 48 h (P < 0.001, P < 0.001 and P = 0.007, respectively), MDGF at 24 and 48 h (P < 0.001 and P = 0.009, respectively) and PDGFB at 6 h (P = 0.047) in the endometriosis group. "
11/01/2020 - "PFMC from 10 women with endometriosis and 10 control participants were treated with vitamin D3.The gene expression levels of PDGFB, MDGF and EGF were measured 6, 24 and 48 h following vitamin D3 administration using real-time PCR. "

08/01/1986 - "The results of this study have thus demonstrated the importance of alveolar macrophage stimulation and increased production of MDGF in the pathogenesis of bleomycin-induced pulmonary fibrosis. "
02/01/1989 - "Previous work in this laboratory has demonstrated increased secretion of fibroblast growth factor (MDGF) activity by alveolar macrophages obtained from mice with bleomycin-induced pulmonary fibrosis. "
08/01/1986 - "In contrast, bleomycin treatment caused a reduction in alveolar macrophage interleukin-1 (IL-1) production, and NDGA treatment did not alter this reduction, which suggests that MDGF is separate from IL-1 in this case, and that MDGF played a more dominant role, at least in this model of pulmonary fibrosis. "

01/01/1986 - "On the basis of these and other physical and biologic properties, we conclude that growth factor activity found in high levels in the alveolar space following acute lung injury resembles MDGF. "
01/01/1985 - "Because MDGF release could not be induced by direct exposure of freshly isolated macrophages to bleomycin, we suggest that augmented release of MDGF is an indirect feature of acute lung injury in this model."
01/01/1985 - "This macrophage-derived growth factor (MDGF) may be particularly important in controlling the proliferation of mesenchymal cells in the pulmonary interstitium following acute lung injury. "

12/10/1982 - "In this instance both PDGF and MDGF could play important roles, since platelets have been associated with the early injury phenomenon and macrophages appear to be present in virtually all phases of the development of the lesions of atherosclerosis from the fatty streak to the fibrous plaque and the complicated lesion. "
09/01/1981 - "The relationship of MDGF to other monocyte products and its potential importance in wound repair and atherogenesis are discussed."

07/01/1992 - "These data demonstrate the changing levels of PDGF and MDGF in human wound fluid over time, supporting the cascade model of wound repair. "
09/01/1981 - "The relationship of MDGF to other monocyte products and its potential importance in wound repair and atherogenesis are discussed."
07/01/1992 - "By demonstrating that MDGF acts on cell lines unresponsive to the PDGF AA found in wound fluid, these data suggest that MDGF may also play an important role in wound healing."
07/01/1992 - "The biologic activity of MDGF was assayed with a cell line that is unresponsive to the PDGF AA found in wound fluid. "
07/01/1992 - "The chemotactic and mitogenic potential of purified wound fluid containing PDGF AA and MDGF was determined on a responsive cell line. "