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spermatid transition proteins

small basic transition protein; amino acid sequence in first source
Also Known As:
TNP1 protein, human; TNP2 protein, human; TP1 (spermatid); Tnp1 protein, mouse; Tnp1 protein, rat; nuclear transition protein 1 (TP1); nuclear transition protein 2; spermatid nuclear transition protein 1, human; spermatid transition protein 1; spermatid transition protein 2; transition protein 1; transition protein 1 (during histone to protamine replacement), human; transition protein 1, mouse; transition protein 1, rat; transition protein 2; transition protein 2 (during histone to protamine replacement), human; transition protein 2, human; transition protein TP1; transition protein TP2
Networked: 8 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Allam, Jean-Pierre: 1 article (01/2022)
2. Becker, Ivonne: 1 article (01/2022)
3. Bedford, Erin: 1 article (01/2022)
4. Eckhardt, Matthias: 1 article (01/2022)
5. Flannigan, Ryan: 1 article (01/2022)
6. Robinson, Meghan: 1 article (01/2022)
7. Sylvester, Marc: 1 article (01/2022)
8. Wang-Eckhardt, Lihua: 1 article (01/2022)
9. Willerth, Stephanie M: 1 article (01/2022)
10. Witherspoon, Luke: 1 article (01/2022)

Related Diseases

1. Azoospermia
02/01/2016 - "Expressions of DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (DDX4), deleted in azoospermia like (DAZL), transition protein 2 (TP2), proliferating cell nuclear antigen (PCNA) and 5-Bromo-20-deoxyuridine (BrdU) were assessed. "
01/01/2022 - "Reverse transcription qualitative polymerase chain reaction analysis showed that after 12 days in spermatogenic media, the bioprints substantially up-regulated spermatogenic gene expression on par with nonbioprinted controls and showed a particularly significant improvement in genes involved in spermatogonial stem cell maintenance: inhibitor of deoxyribonucleic acid binding 4 by 365-fold; fibroblast growth factor 3 by 94,152-fold; stem cell growth factor receptor KIT by twofold; stimulated by retinoic acid 8 by 125-fold; deleted in azoospermia-like by 114-fold; synaptonemal complex protein 3 by sevenfold; zona pellucida binding protein by twofold; transition protein 1 by 2,908-fold; and protamine 2 by 11-fold. "
04/01/2017 - "Quantitative polymerase chain reaction analysis revealed that 20%-40% CCM induced the highest expression of primordial germ cell-specific (deleted in Azoospermia- like (Dazl), dead (Asp-Glu-Ala-Asp) box polypeptide 4 (Vasa also known as DDX4) and promyelocytic leukemia zinc finger protein (Plzf)); meiotic (synaptonemal complex protein 3 (Sycp3), mutl homolog I (Mlh1), transition protein 1/2 (Tnp1/2) and protamine 2 (Prm2); spermatocyte-specific boule-like RNA binding protein (Boule) and tektin 1 (Tekt1)) and oocyte-specific growth differentiation factor 9 (Gdf9) and zona pellucida 2 /3 (Zp2/3)) genes over 8-14 days in culture. "
2. Male Infertility (Male Sterility)
3. Infertility (Sterility)
4. Teratozoospermia

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. protamine 2
3. Fibroblast Growth Factor 3
4. Growth Factor Receptors
5. Tretinoin (Retinoic Acid)
6. DNA (Deoxyribonucleic Acid)
7. Carrier Proteins (Binding Protein)
8. Peptides (Polypeptides)
9. spermatid transition proteins
10. aspartylglutamate