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HC Red No. 3

Also Known As:

2-((4-amino-2-nitrophenyl)amino)ethanol

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Diamines: 518
      - Phenylenediamines: 6
        HC Red No. 3: 1
  - Aniline Compounds: 46
    - Phenylenediamines: 6
      - HC Red No. 3: 1

Related Diseases

1.	Carcinogenesis 01/01/1986 - "Both sexes of both species may have been able to tolerate higher doses of HC Red No. 3. Therefore, the sensitivity of these studies for detecting chese studies for detecting carcinogenesis may have been limited. " 01/01/1986 - "An audit of the experimental data was conducted for these 2-year toxicology and carcinogenesis studies on HC Red No. 3. No data discrepancies were found that influenced the final interpretations. " 01/01/1986 - "NTP Toxicology and Carcinogenesis Studies of HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol] (CAS No. 2871-01-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies)." 01/01/1986 - "oxicology and carcinogenesis studies of HC Red No. 3 (97% pure), a semipermanent hair dye, were conducted by administering the chemical in corn oil by gavage for 105 weeks to groups of 50 male and 50 female F344/N rats and for 104 weeks to groups of 50 male and 50 female B6C3F1 mice. "
2.	Body Weight (Weight, Body) 01/01/1986 - "In the 2-year studies, the administration of HC Red No. 3 did not affect body weight gains of male or female rats or mice. "
3.	Reproductive Tract Infections 01/01/1986 - "Survival of male and female rats and mice was not reduced by administration of HC Red No. 3. The survival of female mice, including vehicle controls, was reduced relative to historical survival rates due to a reproductive tract infection. "
4.	Neoplasms (Cancer) 01/01/1986 - "Largely because of the lack of a dose response, the increased incidence in the low dose females was not considered to be due to HC Red No. 3. No increased incidences of neoplasms were seen in male rats. "

Related Drugs and Biologics

1.	Hair Dyes
2.	Corn Oil (Oil, Corn)
3.	Ethanol (Ethyl Alcohol)